Evidence from physical sciences in oncology increasingly suggests that the interplay
between the biophysical tumor microenvironment and genetic regulation has significant …

An increasing number of studies have demonstrated the significant roles of the interplay
between microenvironmental mechanics in tissues and biochemical-genetic activities in …

Biomechanical forces are of fundamental importance in biology, diseases, and medicine.
Mechanobiology is an emerging interdisciplinary field that studies how biological …

A fundamental question in mechanobiology is how living cells sense extracellular
mechanical stimuli in the context of cell physiology and pathology. The cellular mechano …

Automatic operations of multi-functional and time-lapse live-cell imaging are necessary for
the biomedical science community to study active, multi-faceted, and long-term biological …

Genetically encoded calcium indicators (GECIs) and high-resolution confocal microscopy
enable dynamic visualization of calcium signals in cells and tissues. Two-dimensional and …