Parkinson's disease (PD) is a common neurodegenerative disease characterized
pathologically by dopaminergic neuron loss and the formation of Lewy bodies, which are …

Numerous basic studies have reported on the neuroprotective properties of several purine
derivatives such as caffeine and uric acid (UA). Epidemiological studies have also shown …

Objective To investigate molecular biomarkers of a‐synuclein and tau aggregation,
autophagy, and inflammation in the saliva of de novo Parkinson's disease (PD) patients in …

Neurological disorders pose a great threat to social health and are a major cause for
mortality and morbidity. Effective drug development complemented with the improved drug …

Background Non-genetic risk factors play a relevant role in Parkinson's disease (PD)
development but the relationship between these factors and PD clinical features is unknown …

Introduction Circadian rhythms (CRs) orchestrate intrinsic 24-hour oscillations which
synchronize an organism's physiology and behaviour with respect to daily cycles. CR …

Parkinson's disease (PD) is a neurodegenerative disorder characterized by diverse
symptoms, where accurate diagnosis remains challenging. Traditional clinical observation …

Current research efforts on neurodegenerative diseases are focused on identifying novel
and reliable biomarkers for early diagnosis and insight into disease progression. Salivary …

Objective There is a lack of systematic studies on salivary metabolomic profiles in burning
mouth syndrome (BMS); metabolomics could help explore BMS pathogenesis. We aimed to …

This study aimed to evaluate the effect of caffeine on cognitive parameters in premenstrual
syndrome women of childbearing age undergoing caffeine withdrawal, observing the …