Oxidative stress (OS) is a condition that occurs as a result of an imbalance between the
production of reactive oxygen species (ROS) and the body's ability to detoxify and neutralize …

Abstract Uncoupling protein 1 (UCP1) has been discovered as a possible target for obesity
treatment because of its widespread distribution in the inner mitochondrial membrane of …

Objective High intake of caffeoylquinic acid (CQA)-rich dietary supplements, such as green
coffee bean extracts, offers health-promoting effects on maintaining metabolic homeostasis …

Background. The prevalence of Hashimoto's thyroiditis (HT) among women with polycystic
ovary syndrome (PCOS) is higher than in the general female population, but the factors …

Temperature has been recognized as an important environmental factor affecting the
composition and function of gut microbiota (GM). Although research on high-temperature …

Laboratory rodents and cold-adapted animals in the wild use a significant amount of the
energy derived from food intake for heat generation. Thermogenesis involving mitochondrial …

Adipose tissue can be divided into white adipose tissue (WAT), brown adipose tissue (BAT),
and beige adipose tissue, according to the differences in morphology. WAT acts as a buffer …

The robustness of scientific results is partly based on their reproducibility. Working with
animal models, particularly in the field of metabolism, requires to avoid any source of stress …

Objective Ferritin, the principal iron storage protein, is essential to iron homeostasis. How
iron homeostasis affects the adipose tissue is not well understood. We investigated the role …

Excessive food intake leads to lipid accumulation in white adipose tissue, triggering
inflammation, cellular stress, insulin resistance, and metabolic syndrome. In contrast, the …