Deep brain stimulation of the subthalamic nucleus (STN‐DBS) is a promising palliative
option for patients with refractory epilepsy. However, crucial questions remain unanswered …

Objectives Epilepsy continues to provide challenges to clinicians, as a significant proportion
of patients continue to suffer from seizures despite medical and surgical treatments …

Objective Responsive neurostimulation is an effective therapy for patients with refractory
mesial temporal lobe epilepsy. However, clinical outcomes are variable, few patients …

Background Deep brain stimulation (DBS) is an established clinical therapy and
computational models have played an important role in advancing the technology. Patient …

Introduction One-third of patients with epilepsy continue to have seizures despite
antiepileptic medications. Some of these refractory patients may not be candidates for …

Object Epilepsy surgery is at the cusp of a transformation due to the convergence of
advancements in multiple technologies. Emerging neuromodulatory therapies offer the …

Purpose There is significant variation in how patients respond to cortical electrical
stimulation. It has been hypothesized that individual demographic and pathologic factors …

Purpose Minimally invasive treatment of solid cancers, especially in the breast and liver,
remains clinically challenging, despite a variety of treatment modalities, including …

BACKGROUND Responsive neuromodulation (RNS) is a treatment option for patients with
medically refractory bilateral mesial temporal lobe epilepsy (MTLE). A paucity of data exists …

Electrical stimulation in the treatment of epilepsy has been tried in numerous forms and with
a variety of targets. Some of these, such as anterior thalamic stimulation, responsive cortical …