A Costa, M Pinheiro, J Magalhães, R Ribeiro… - Advanced drug delivery …, 2016 - Elsevier
Recent estimates indicate that tuberculosis (TB) is the leading cause of death worldwide, alongside the human immunodeficiency virus (HIV) infection. The current treatment is …
IP Kaur, H Singh - Journal of Controlled Release, 2014 - Elsevier
With almost 30% of the world population suffering from tuberculosis (TB) including its resurgence in the developed world, better management of this global threat is highly …
Tuberculosis (TB) has gone from being a forgotten disease to a modern and recrudescent pathology from past decades. Some clinical problems and challenges associated with …
MS El-Ridy, A Abdelbary, EA Nasr… - Drug development …, 2011 - Taylor & Francis
It is estimated that more than one-third of the world population is infected with Mycobacterium tuberculosis. Pyrazinamide (PZA) plays a unique role in shortening therapy …
D He, P Deng, L Yang, Q Tan, J Liu, M Yang… - Colloids and surfaces B …, 2013 - Elsevier
A hydrophobic drug, rifampin (RFP), was molecularly encapsulated into hydroxylpropyl-β- cyclodextrin (HCD) to form a molecular inclusion complex (MRICD) with higher solubility and …
KR Bittleman, S Dong, M Roman, YW Lee - ACS omega, 2018 - ACS Publications
The study evaluates cellulose nanocrystals (CNCs) as nanocarriers for targeted, intracellular delivery of molecular agents. CNCs were labeled with fluorescein-5′-isothiocyanate as an …
D Traini, PM Young - Therapeutic delivery, 2017 - Taylor & Francis
Worldwide, tuberculosis (TB) has 86% treatment success rate in new cases, leaving more than 1 million new patients without a cure [1]. Thus, the need for both shorter treatment …
The recurrent development of resistance to antimicrobial agents threatens the ability for successful treatment of infectious diseases. Hydrophobic antibiotics such as rifampicin (Rif) …