Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles

AP Singh, A Biswas, A Shukla, P Maiti - Signal transduction and …, 2019 - nature.com
The application of nanomedicines is increasing rapidly with the promise of targeted and
efficient drug delivery. Nanomedicines address the shortcomings of conventional therapy, as …

The formulation of nanomedicines for treating tuberculosis

A Costa, M Pinheiro, J Magalhães, R Ribeiro… - Advanced drug delivery …, 2016 - Elsevier
Recent estimates indicate that tuberculosis (TB) is the leading cause of death worldwide,
alongside the human immunodeficiency virus (HIV) infection. The current treatment is …

Nanostructured drug delivery for better management of tuberculosis

IP Kaur, H Singh - Journal of Controlled Release, 2014 - Elsevier
With almost 30% of the world population suffering from tuberculosis (TB) including its
resurgence in the developed world, better management of this global threat is highly …

Current nanotechnological strategies for effective delivery of bioactive drug molecules in the treatment of tuberculosis

M Kaur, T Garg, G Rath, A Goyal - Critical Reviews™ in …, 2014 - dl.begellhouse.com
Tuberculosis (TB) has gone from being a forgotten disease to a modern and recrudescent
pathology from past decades. Some clinical problems and challenges associated with …

Niosomal encapsulation of the antitubercular drug, pyrazinamide

MS El-Ridy, A Abdelbary, EA Nasr… - Drug development …, 2011 - Taylor & Francis
It is estimated that more than one-third of the world population is infected with
Mycobacterium tuberculosis. Pyrazinamide (PZA) plays a unique role in shortening therapy …

Molecular encapsulation of rifampicin as an inclusion complex of hydroxypropyl-β-cyclodextrin: Design; characterization and in vitro dissolution

D He, P Deng, L Yang, Q Tan, J Liu, M Yang… - Colloids and surfaces B …, 2013 - Elsevier
A hydrophobic drug, rifampin (RFP), was molecularly encapsulated into hydroxylpropyl-β-
cyclodextrin (HCD) to form a molecular inclusion complex (MRICD) with higher solubility and …

Folic acid-conjugated cellulose nanocrystals show high folate-receptor binding affinity and uptake by KB and breast cancer cells

KR Bittleman, S Dong, M Roman, YW Lee - ACS omega, 2018 - ACS Publications
The study evaluates cellulose nanocrystals (CNCs) as nanocarriers for targeted, intracellular
delivery of molecular agents. CNCs were labeled with fluorescein-5′-isothiocyanate as an …

Drug delivery for tuberculosis: is inhaled therapy the key to success?

D Traini, PM Young - Therapeutic delivery, 2017 - Taylor & Francis
Worldwide, tuberculosis (TB) has 86% treatment success rate in new cases, leaving more
than 1 million new patients without a cure [1]. Thus, the need for both shorter treatment …

[PDF][PDF] 脂质体制备技术及其研究进展

刘晓谦, 王锦玉, 仝燕, 王智民 - 中国药学杂志, 2011 - journal11.magtechjournal.com
目的综述脂质体制备技术的研究进展及其发展前景. 方法以近年来的研究文献为基础,
结合药物的性质, 工艺要求, 对脂质体的制备方法进行综述, 并对各种方法的优缺点进行分析 …

Simultaneous liposomal encapsulation of antibiotics and proteins: Co-loading and characterization of rifampicin and Human Serum Albumin in soy-liposomes

AM Bapolisi, CI Nkanga, RB Walker… - Journal of Drug Delivery …, 2020 - Elsevier
The recurrent development of resistance to antimicrobial agents threatens the ability for
successful treatment of infectious diseases. Hydrophobic antibiotics such as rifampicin (Rif) …