E-cadherin and P-cadherin are major contributors to cell–cell adhesion in epithelial tissues,
playing pivotal roles in important morphogenetic and differentiation processes during …

In humans, cell fusion is restricted to only a few cell types under normal conditions. In the
placenta, cell fusion is a critical process for generating syncytiotrophoblast: the giant …

The increasing use of nanoparticles in medicine has raised concerns over their ability to
gain access to privileged sites in the body. Here, we show that cobalt–chromium …

Background Epidemiological and animal studies provide compelling indications that
environmental and engineered nanomaterials (NMs) pose a risk for pregnancy, fetal …

Implantation failure and inadequate placental development are important contributors to
infertility, recurrent miscarriage, and other pregnancy-related problems in women. Better …

The outbreak of the coronavirus disease 2019 (COVID-19) pandemic has caused a global
public health crisis. Viral infections may predispose pregnant women to a higher rate of …

Carcinomas, cancers of epithelial origin, constitute the majority of all cancers. Loss of
epithelial characteristics is an early step in carcinoma progression. Malignant transformation …

STUDY QUESTION How does the human embryo breach the endometrial epithelium at
implantation? SUMMARY ANSWER Embryo attachment to the endometrial epithelium …

Colonisation of the maternal uterine wall by the trophoblast involves a series of alterations in
the behaviour and morphology of trophoblast cells. Villous cytotrophoblast cells change from …

ABSTRACT P-cadherin is a cell-cell adhesion molecule, whose expression is highly
associated with undifferentiated cells in normal adult epithelial tissues, as well as with poorly …