Immune responses are generally divided into innate and adaptive responses, and the
efficacy of one is thought to be independent of the other. The regulation of immune …

T cells mediate antigen-specific immune responses to disease through the specificity and
diversity of their clonotypic T cell receptors (TCRs). Determining the spatial distributions of T …

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TLRs are an evolutionarily conserved family of cell membrane proteins believed to play a
significant role in innate immunity and the response to tissue injury, including that induced …

Recent studies have implicated a possible role for NK cells in regulating dendritic cells (DC)
in vitro. In the present study, we demonstrate that immature DC are rapidly eliminated by NK …

Tumor-associated immunosuppressive strategies, such as lack of tumor antigen recognition
and failure of lymphocyte activation and homing, resist the development of tumor-specific …

Natural killer (NK) cells are innate lymphoid cells (ILC) known for their ability to recognize
and rapidly eliminate infected or transformed cells. Consequently, NK cells are fundamental …

Dendritic cell (DC)-based vaccination represents a promising approach to harness the
specificity and potency of the immune system to combat cancer. Finding optimal strategies …

In addition to maintaining cell homeostasis under physiological and stress conditions, some
heat shock proteins (HSPs) are potent inducers of immunity and have been harnessed as …

Glucose-regulated protein 170 (GRP170) is the largest member of glucose-regulated protein
family that resides in the endoplasmic reticulum (ER). As a component of the ER chaperone …