Although eosinophilic inflammation is characteristic of asthma pathogenesis, neutrophilic
inflammation is also marked, and eosinophils and neutrophils can coexist in some cases …

Abstract Purpose of Review The study of microRNA in asthma has revealed a vibrant new
level of gene regulation underlying asthma pathology. Several miRNAs have been shown to …

Abstract Rationale and Objective Plasma extracellular vesicles (EVs) represent a vital
source of molecular information about health and disease states. Due to their heterogenous …

Extracellular vesicles (EVs) being defined as lipid-bilayer encircled particles are released by
almost all known mammalian cell types and represent a heterogenous set of cell fragments …

Eosinophilic esophagitis (EoE) is a chronic, Th2-inflammatory disease of the esophagus that
can severely affect food intake. Currently, diagnosis and assessing response to treatment of …

Pulmonary disease such as chronic obstructive pulmonary disease (COPD), asthma,
pulmonary fibrosis and pulmonary hypertension are the leading cause of deaths. More …

There is a long-standing appreciation among environmental engineers and scientists
regarding the importance of biologically derived colloidal particles and their environmental …

Extracellular vesicles (EVs) gain increasing attention due to their (patho-) physiological role
in intercellular signaling, specifically in the communication between distant organs. Recent …

Severe asthma (SA) is a chronic inflammatory disease of the airways. Due to the extreme
heterogeneity of symptoms, new biomarkers are currently needed. MiRNAs are non-coding …

Mesenchymal stem cells (MSCs) are a type of cell capable of regulating the immune system,
as well as exhibiting self-renewal and multi-lineage differentiation potential. Mesenchymal …