Peripheral nerve repair and regeneration remains among the greatest challenges in tissue
engineering and regenerative medicine. Even though peripheral nerve injuries (PNIs) are …

Hepatocyte growth factor (HGF) and its tyrosine kinase receptor, encoded by the MET
cellular proto-oncogene, are expressed in the nervous system from pre-natal development …

The intrinsic ability of peripheral nerves to regenerate after injury is extremely limited,
especially in case of severe injury. This often leads to poor motor function and permanent …

Peripheral nerve injuries can be extremely debilitating, resulting in sensory and motor loss-
of-function. Endogenous repair is limited to non-severe injuries in which transection of …

Injuries and diseases of the peripheral nervous system (PNS) are common but frequently
irreversible. It is often but mistakenly assumed that peripheral neuron regeneration is robust …

Peripheral nerve injuries persist as a major clinical issue facing the US population and can
be caused by stretch, laceration, or crush injuries. Small nerve gaps are simple to treat, and …

Regeneration is a fundamental process attributed to the functions of adult stem cells. In the
last decades, delivery of suspended adult stem cells is widely adopted in regenerative …

Vascular endothelial growth factor (VEGF) and fibroblast growth factor 2 (FGF2) are well-
known growth factors involved in the regeneration of various tissues and organs, including …

Regenerative medicine that had emerged as a scientific and medical discipline at end of
20th century uses cultured cells and tissue-engineered structures for transplantation into …

To address limitations in current approaches for treating large peripheral nerve defects, the
presented study evaluated the feasibility of functional material-mediated physical stimuli on …