Pathogenesis of the Pseudomonas aeruginosa Biofilm: A Review

FF Tuon, LR Dantas, PH Suss, VS Tasca Ribeiro - Pathogens, 2022 - mdpi.com
Pseudomonas aeruginosa is associated with several human infections, mainly related to
healthcare services. In the hospital, it is associated with resistance to several antibiotics …

Microbial biofilm: formation, architecture, antibiotic resistance, and control strategies

MA Rather, K Gupta, M Mandal - Brazilian Journal of Microbiology, 2021 - Springer
The assembly of microorganisms over a surface and their ability to develop resistance
against available antibiotics are major concerns of interest. To survive against harsh …

Developing natural products as potential anti-biofilm agents

L Lu, W Hu, Z Tian, D Yuan, G Yi, Y Zhou, Q Cheng… - Chinese medicine, 2019 - Springer
Biofilm is a natural form of bacterial growth ubiquitously in environmental niches. The biofilm
formation results in increased resistance to negative environmental influences including …

Quorum sensing: a prospective therapeutic target for bacterial diseases

Q Jiang, J Chen, C Yang, Y Yin… - BioMed Research …, 2019 - Wiley Online Library
Bacterial quorum sensing (QS) is a cell‐to‐cell communication in which specific signals are
activated to coordinate pathogenic behaviors and help bacteria acclimatize to the …

Plant secondary metabolites in the battle of drugs and drug-resistant bacteria: new heroes or worse clones of antibiotics?

CL Gorlenko, HY Kiselev, EV Budanova… - Antibiotics, 2020 - mdpi.com
Infectious diseases that are caused by bacteria are an important cause of mortality and
morbidity in all regions of the world. Bacterial drug resistance has grown in the last decades …

Pseudomonas aeruginosa Biofilms: Host Response and Clinical Implications in Lung Infections

NM Maurice, B Bedi, RT Sadikot - American journal of respiratory …, 2018 - atsjournals.org
Pseudomonas aeruginosa is a major health challenge that causes recalcitrant multidrug-
resistant infections, especially in immunocompromised and hospitalized patients. P …

Quorum sensing inhibitors as antipathogens: biotechnological applications

VC Kalia, SKS Patel, YC Kang, JK Lee - Biotechnology advances, 2019 - Elsevier
The mechanisms through which microbes communicate using signal molecules has inspired
a great deal of research. Microbes use this exchange of information, known as quorum …

Quorum quenching: role in nature and applied developments

C Grandclément, M Tannières, S Moréra… - FEMS microbiology …, 2016 - academic.oup.com
Quorum sensing (QS) refers to the capacity of bacteria to monitor their population density
and regulate gene expression accordingly: the QS-regulated processes deal with …

Plant natural products targeting bacterial virulence factors

LN Silva, KR Zimmer, AJ Macedo, DS Trentin - Chemical reviews, 2016 - ACS Publications
Decreased antimicrobial efficiency has become a global public health issue. The paucity of
new antibacterial drugs is evident, and the arsenal against infectious diseases needs to be …

Exploiting quorum sensing to confuse bacterial pathogens

B LaSarre, MJ Federle - Microbiology and molecular biology …, 2013 - Am Soc Microbiol
Cell-cell communication, or quorum sensing, is a widespread phenomenon in bacteria that
is used to coordinate gene expression among local populations. Its use by bacterial …