Using the Alzheimer's Disease Neuroimaging Initiative to improve early detection, diagnosis, and treatment of Alzheimer's disease

DP Veitch, MW Weiner, PS Aisen… - Alzheimer's & …, 2022 - Wiley Online Library
Abstract Introduction The Alzheimer's Disease Neuroimaging Initiative (ADNI) has
accumulated 15 years of clinical, neuroimaging, cognitive, biofluid biomarker and genetic …

Neuroimaging modalities in Alzheimer's disease: diagnosis and clinical features

JH Kim, M Jeong, WR Stiles, HS Choi - International journal of molecular …, 2022 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disease causing progressive cognitive
decline until eventual death. AD affects millions of individuals worldwide in the absence of …

Generalizable deep learning model for early Alzheimer's disease detection from structural MRIs

S Liu, AV Masurkar, H Rusinek, J Chen, B Zhang… - Scientific reports, 2022 - nature.com
Early diagnosis of Alzheimer's disease plays a pivotal role in patient care and clinical trials.
In this study, we have developed a new approach based on 3D deep convolutional neural …

[HTML][HTML] Gamma frequency sensory stimulation in mild probable Alzheimer's dementia patients: Results of feasibility and pilot studies

D Chan, HJ Suk, BL Jackson, NP Milman, D Stark… - PloS one, 2022 - journals.plos.org
Non-invasive Gamma ENtrainment Using Sensory stimulation (GENUS) at 40Hz reduces
Alzheimer's disease (AD) pathology such as amyloid and tau levels, prevents cerebral …

MADGAN: Unsupervised medical anomaly detection GAN using multiple adjacent brain MRI slice reconstruction

C Han, L Rundo, K Murao, T Noguchi, Y Shimahara… - BMC …, 2021 - Springer
Background Unsupervised learning can discover various unseen abnormalities, relying on
large-scale unannotated medical images of healthy subjects. Towards this, unsupervised …

[HTML][HTML] Layer-wise relevance propagation for explaining deep neural network decisions in MRI-based Alzheimer's disease classification

M Böhle, F Eitel, M Weygandt, K Ritter - Frontiers in aging …, 2019 - frontiersin.org
Deep neural networks have led to state-of-the-art results in many medical imaging tasks
including Alzheimer's disease (AD) detection based on structural magnetic resonance …

Automatic detection of Alzheimer's disease progression: An efficient information fusion approach with heterogeneous ensemble classifiers

S El-Sappagh, F Ali, T Abuhmed, J Singh, JM Alonso - Neurocomputing, 2022 - Elsevier
Predicting Alzheimer's disease (AD) progression is crucial for improving the management of
this chronic disease. Usually, data from AD patients are multimodal and time series in …

Two-stage deep learning model for Alzheimer's disease detection and prediction of the mild cognitive impairment time

S El-Sappagh, H Saleh, F Ali, E Amer… - Neural Computing and …, 2022 - Springer
Alzheimer's disease (AD) is an irreversible neurodegenerative disease characterized by
thinking, behavioral and memory impairments. Early prediction of conversion from mild …

Structural magnetic resonance imaging for the early diagnosis of dementia due to Alzheimer's disease in people with mild cognitive impairment

G Lombardi, G Crescioli, E Cavedo… - Cochrane Database …, 2020 - cochranelibrary.com
Background Mild cognitive impairment (MCI) due to Alzheimer's disease is the symptomatic
predementia phase of Alzheimer's disease dementia, characterised by cognitive and …

Microbiota modulation as preventative and therapeutic approach in Alzheimer's disease

L Bonfili, V Cecarini, O Gogoi, C Gong… - The FEBS …, 2021 - Wiley Online Library
The gut microbiota coevolves with its host, and numerous factors like diet, lifestyle, drug
intake and geographical location continuously modify its composition, deeply influencing …