Amyloidosis is a deleterious condition caused by abnormal amyloid fibril build-up in living
tissues. To date, 42 proteins that are linked to amyloid fibrils have been discovered. Amyloid …

Musculoskeletal disorders are the most common reason of chronic pain and disability,
representing an enormous socioeconomic burden worldwide. In this review, new biomedical …

The unique structure of the Achilles tendon, combining three smaller sub-tendons, enhances
movement efficiency by allowing individual control from connected muscles. This requires …

High operational costs of modern medical devices and the required specialized, skilled
personnel with certifications to operate most medical instrumentation remains a challenge …

Non-enzymatic glycation is a post-translational modification of long-lived matrix proteins
such as type I collagen. It occurs during aging and leads to the formation of advanced …

The establishment of various molecular, physiological, and genetic markers for cellular
senescence and aging‐associated conditions has progressed the aging study. To identify …

The purpose of this study is to determine whether age-related changes to tendon matrix
molecules can be detected using Raman spectroscopy. Raman spectra were collected from …

Abstract Background The NHS spends£ 4.3 billion annually to address musculoskeletal
conditions, encompassing age-related bone disorders like osteoarthritis and osteoporosis …

In Greek mythology, Achilles, the Greek hero, is almost invulnerable—except for his Achilles
heel, whose injury resulted in his death. How could a tendon injury take such a prominent …