The SARS-CoV-2 neutralizing antibody response to SD1 and its evasion by BA. 2.86

D Zhou, P Supasa, C Liu, A Dijokaite-Guraliuc… - Nature …, 2024 - nature.com
Under pressure from neutralising antibodies induced by vaccination or infection the SARS-
CoV-2 spike gene has become a hotspot for evolutionary change, leading to the failure of all …

The accomplices: Heparan sulfates and N-glycans foster SARS-CoV-2 spike: ACE2 receptor binding and virus priming

G Paiardi, M Ferraz, M Rusnati, RC Wade - Proceedings of the National …, 2024 - pnas.org
Although it is well established that the SARS-CoV-2 spike glycoprotein binds to the host cell
ACE2 receptor to initiate infection, far less is known about the tissue tropism and host cell …

Analysis of emergent bivalent antibody binding identifies the molecular reach as a critical determinant of SARS-CoV-2 neutralisation potency

A Huhn, D Nissley, DB Wilson, M Kutuzov, R Donat… - bioRxiv, 2023 - biorxiv.org
Key functions of antibodies, such as viral neutralisation, depend on bivalent binding but the
factors that influence it remain poorly characterised. Here, we develop and employ a new …