Although it is well established that the SARS-CoV-2 spike glycoprotein binds to the host cell ACE2 receptor to initiate infection, far less is known about the tissue tropism and host cell …
A Huhn, D Nissley, DB Wilson, M Kutuzov, R Donat… - bioRxiv, 2023 - biorxiv.org
Key functions of antibodies, such as viral neutralisation, depend on bivalent binding but the factors that influence it remain poorly characterised. Here, we develop and employ a new …