Introduction The therapeutic targeting of the ubiquitin-proteasome pathway (UPP) through
inhibitors of the 20S proteasome core proteolytic activities has revolutionized the treatment …

Simple Summary This mini-review summarizes the up-to-date progress in developing
anticancer therapies based on cutting-edge strategies employing short peptides. This work …

Background: The effect of proteasome inhibitors on atherosclerosis is known to vary
depending on the atherosclerosis stage. Previous studies have shown that the highest …

The investigation of potential self-assembled peptides as carriers for the delivery of
anticancer drug Bortezomib is the topic of the present study. The self-assembly of …

This study reports the passive diffusion (in vitro) of silver nanoparticles (SNPs) and those of
the amino acids tryptophan, phenylalanine, tyrosine across a biological membrane model …

The interactions involving the side chains of weakly polar aromatic amino acid residues, eg,
Phenylalanine (Phe), Tyrosine (Tyr) and Tryptophan (Trp) generally reside at the interior of …

Acute myeloid leukaemia is one of the most common form of adult leukaemia with several
kinase mutations. The FLT3-ITD mutation is a common kinase mutation observed in (20 …

A precised and reproducible stability indicating RP-HPLC method was developed for the
simultaneous estimation of hydrochlorothiazide, ramipril and losartan potassium in plasma …

Recombinant DNA (r-DNA) technology or Genetic Engineering is an umbrella term for a set
of experimental techniques that empower specific genes and DNA sequences to be …

Synthetic approaches to construction of designed proteins have primarily relied on the
known secondary structure-forming propensities of amino acids, gleaned from analysis of …