Abstract Introduction The protein Klotho (KL) was first discovered in KL-deficient mice, which
developed a syndrome similar to premature aging in humans. Since then, KL has been …

The endocannabinoid system (ECS) is a highly versatile signaling system within the nervous
system. Despite its widespread localization, its functions within the context of distinct neural …

Abstract Purpose of Review Review the current evidence on biomarkers for bipolar disorder
in the older adults. We conducted a systematic search of PubMed MEDLINE, PsycINFO, and …

Depression is a serious neuropsychiatric disease affecting an increasing number of people
worldwide. Cognitive deficits (including inattention, poor memory, and decision-making …

Current first-line treatments for major depressive disorder (MDD), ie, antidepressant drugs
and psychotherapy, show delayed onset of therapeutic effect as late as 2–3 weeks or more …

With this letter we would like to refer to the review on the topic of neuroplasticity,
hippocampus and depression, in which, however, electroconvulsive therapy (ECT) was …

The kynurenine pathway of tryptophan (Trp) metabolism generates multiple biologically
active metabolites (kynurenines) that have been implicated in neuropsychiatric disorders. It …

Depression is a major mental health disorder, and its pathophysiology is still largely
unknown, as is the action mechanism of electroconvulsive therapy (ECT). Some evidence …

Abnormal activation of the kynurenine and serotonin pathways of tryptophan metabolism is
linked to a host of neuropsychiatric disorders. Concurrently, noninvasive brain stimulation …

Methods All patients with depressive disorders, treated with flumazenil during a course of
ECT in 2019 in a tertiary hospital, were identified through a retrospective chart review …