[HTML][HTML] Extrusion 3D (bio) printing of alginate-gelatin-based composite scaffolds for skeletal muscle tissue engineering

SY Sonaye, EG Ertugral, CR Kothapalli, P Sikder - Materials, 2022 - mdpi.com
Volumetric muscle loss (VML), which involves the loss of a substantial portion of muscle
tissue, is one of the most serious acute skeletal muscle injuries in the military and civilian …

Nanocomposite conductive bioinks based on low-concentration GelMA and MXene nanosheets/gold nanoparticles providing enhanced printability of functional …

S Boularaoui, A Shanti, M Lanotte, S Luo… - ACS Biomaterials …, 2021 - ACS Publications
There is a growing need to develop novel well-characterized biological inks (bioinks) that
are customizable for three-dimensional (3D) bioprinting of specific tissue types. Gelatin …

[HTML][HTML] Fibrogenesis in LAMA2-Related Muscular Dystrophy Is a Central Tenet of Disease Etiology

A Accorsi, ML Cramer, M Girgenrath - Frontiers in molecular …, 2020 - frontiersin.org
LAMA2-related congenital muscular dystrophy, also known as MDC1A, is caused by loss-of-
function mutations in the alpha2 chain of Laminin-211. Loss of this protein interrupts the …

Hippo pathway effectors control cardiac progenitor cell fate by acting as dynamic sensors of substrate mechanics and nanostructure

D Mosqueira, S Pagliari, K Uto, M Ebara… - ACS …, 2014 - ACS Publications
Stem cell responsiveness to extracellular matrix (ECM) composition and mechanical cues
has been the subject of a number of investigations so far, yet the molecular mechanisms …

Bioinspired electrospun dECM scaffolds guide cell growth and control the formation of myotubes

MM Smoak, KJ Hogan, KJ Grande-Allen, AG Mikos - Science Advances, 2021 - science.org
While skeletal muscle has a high capacity for endogenous repair in acute injuries,
volumetric muscle loss can leave long-lasting or permanent structural and functional deficits …

Precision 3D‐printed cell scaffolds mimicking native tissue composition and mechanics

A Erben, M Hörning, B Hartmann… - Advanced …, 2020 - Wiley Online Library
Cellular dynamics are modeled by the 3D architecture and mechanics of the extracellular
matrix (ECM) and vice versa. These bidirectional cell‐ECM interactions are the basis for all …

[HTML][HTML] TGF-β Regulates Collagen Type I Expression in Myoblasts and Myotubes via Transient Ctgf and Fgf-2 Expression

MMG Hillege, RA Galli Caro, C Offringa, GMJ de Wit… - Cells, 2020 - mdpi.com
Transforming Growth Factor β (TGF-β) is involved in fibrosis as well as the regulation of
muscle mass, and contributes to the progressive pathology of muscle wasting disorders …

[HTML][HTML] Characterization of gelatin hydrogels cross-linked with microbial transglutaminase as engineered skeletal muscle substrates

D Gupta, JW Santoso, ML McCain - Bioengineering, 2021 - mdpi.com
Engineered in vitro models of skeletal muscle are essential for efficiently screening drug
safety and efficacy. However, conventional culture substrates poorly replicate physical …

[HTML][HTML] Tuning myogenesis by controlling gelatin hydrogel properties through hydrogen peroxide-mediated cross-linking and degradation

W Mubarok, KCML Elvitigala, S Sakai - Gels, 2022 - mdpi.com
Engineering skeletal muscle tissue in vitro is important to study the mechanism of
myogenesis, which is crucial for regenerating muscle cells. The physicochemical properties …

The nanofibrous PAN-PANi scaffold as an efficient substrate for skeletal muscle differentiation using satellite cells

S Hosseinzadeh, M Mahmoudifard… - Bioprocess and …, 2016 - Springer
Among polymers, polyaniline (PANi) has been introduced as a good candidate for muscle
regeneration due to high conductivity and also biocompatibility. Herein, for the first time, we …