Inflammation is a hallmark of virtually all liver diseases, such as liver cancer, fibrosis,
nonalcoholic steatohepatitis, alcoholic liver disease, and cholangiopathies. Liver …

Viruses manipulate cell biology to utilize monocytes/macrophages as vessels for
dissemination, long-term persistence within tissues and virus replication. Viruses enter cells …

Macrophages facilitate essential homeostatic functions eg, endocytosis, phagocytosis, and
signaling during inflammation, and express a variety of scavenger receptors including …

Hepatitis C virus (HCV) infection is the major risk factor for liver cirrhosis and hepatocellular
carcinoma (HCC). The mechanisms of HCC initiation, growth, and metastasis appear to be …

Nearly 2.3 million individuals worldwide are coinfected with human immunodeficiency virus
(HIV) and hepatitis C virus (HCV). Odds of HCV infection are six times higher in people living …

Sofosbuvir‐based direct‐acting antiviral (DAA) therapy generally cures chronic hepatitis C
(CHC) infections, however, the effects on the underlying liver disease and the potential rate …

Macrophages are essential components of the human host immune system, which upon
activation facilitates a broad pallet of immunomodulatory events including release of pro-or …

Steatosis is a condition of hepatic fat overload that is associated with overweight and the
metabolic syndrome. Nonalcoholic fatty liver disease (NAFLD) has become the most …

METHODS: We investigated 2 independent PSC cohorts from Oslo (n= 138) and Helsinki
(n= 159) and analyzed blood sCD163 and sMR levels. The Mayo score, Enhanced Liver …

Hepatitis C virus (HCV) has spread worldwide, and it is responsible for potentially severe
chronic liver disease and primary liver cancer. Chronic infection remains for life if not …