Background: Thiazole is a good pharmacophore nucleus due to its various pharmaceutical
applications. Its derivatives have a wide range of biological activities such as antioxidant …

In the last few decades, considerable progress has been made in anticancer agents
development, and several new anticancer agents of natural and synthetic origin have been …

A Hybrid drug which comprises the incorporation of two drug pharmacophores in one single
molecule are basically designed to interact with multiple targets or to amplify its effect …

Heterocycles form, by far, the largest of the classical divisions of organic chemistry.
Moreover, they are of immense importance not only biologically and industrially but also to …

A series of novel compounds carrying 1, 2, 4-triazole scaffold were prepared and evaluated
for their antiproliferative activities against NCI 60 cell line. Compounds 10 (a, c), 11 (ad), and …

The synthesis of some 2-furano-4 (3H)-quinazolinones, diamides (open ring quinazolines),
quinoxalines and their biological evaluation as antitumor agents using National Cancer …

Chalcones have been identified as interesting compounds with cytotoxicity, anti-
inflammatory and antioxidant properties. In the present study, simple methoxychalcones …

The features of the chemistry of 4-thiazolidinone and pyrazole/pyrazolines as
pharmacologically attractive scaffolds were described in a number of reviews in which the …

Cancer is the second leading cause of death worldwide. There is always a huge demand for
novel anticancer drugs and diverse new natural or synthetic compounds are developed …

Thiourea and its derivatives are versatile compounds used in several fields of life ranging
from medicinal to chemosensor applications. In this review article, generally used …