Medicinal plants in Brazil: Pharmacological studies, drug discovery, challenges and perspectives

RC Dutra, MM Campos, ARS Santos… - Pharmacological research, 2016 - Elsevier
This review article focuses on pre-clinical and clinical studies with some selected Brazilian
medicinal plants in different areas of interest, conducted by research groups in Brazil and …

Pharmacologic overview of chlorogenic acid and its metabolites in chronic pain and inflammation

D Bagdas, Z Gul, JA Meade, B Cam… - Current …, 2020 - ingentaconnect.com
Background: Natural phenolic compounds in medicinal herbs and dietary plants are
antioxidants which play therapeutic or preventive roles in different pathological situations …

Evaluation of the analgesic effect of alkaloid extract of Peganum harmala L.: possible mechanisms involved

L Farouk, A Laroubi, R Aboufatima, A Benharref… - Journal of …, 2008 - Elsevier
The seeds of Peganum harmala L.(Pgh)(Zygophyllaceae) have been used in Moroccan
traditional medicine for treatment of a various diseases and to relieve dolorous process. The …

Hypericum spp.: An update on the biological activities and metabolic profiles

M Marrelli, G Statti, F Conforti - Mini reviews in medicinal …, 2020 - ingentaconnect.com
Plants from the genus Hypericum, one genus of the Hypericaceae family, have attracted a lot
of attention for their potential pharmaceutical applications. Most of the studies in the …

Evaluation of the analgesic effect of Echium amoenum Fisch & CA Mey. extract in mice: possible mechanism involved

MR Heidari, EM Azad, M Mehrabani - Journal of ethnopharmacology, 2006 - Elsevier
Echium amoenum Fisch & CA Mey. has been used in Iranian traditional medicine as
demulcent and analgesic in common cold from long ago. In this investigation, the analgesic …

The anti-immobility effect of hyperoside on the forced swimming test in rats is mediated by the D2-like receptors activation

JS Haas, ED Stolz, AH Betti, AC Stein… - Planta …, 2011 - thieme-connect.com
The crude extracts of Hypericum species native to South Brazil showed analgesic and
antidepressant-like effects in rodents. The chemical characterization of these species …

Uliginosin B, a phloroglucinol derivative from Hypericum polyanthemum: a promising new molecular pattern for the development of antidepressant drugs

AC Stein, AF Viana, LG Müller, JM Nunes… - Behavioural Brain …, 2012 - Elsevier
In this study we have demonstrated that cyclohexane extract of Hypericum polyanthemum
(POL) and its main phloroglucinol derivative uliginosin B (ULI) present antidepressant-like …

The Effect of Hypericum perforatum (St. John's Wort) on Experimental Colitis in Rat

T Dost, H Ozkayran, F Gokalp, C Yenisey… - Digestive diseases and …, 2009 - Springer
The aim of the present study was to investigate the effect of Hypericum perforatum (HP) on
the inflammatory and immune response of colonic mucosa in rat with induced inflammatory …

Veterinary herbal medicine: A systems-based approach

SG Wynn, BJ Fougère - Veterinary herbal medicine, 2009 - pmc.ncbi.nlm.nih.gov
This chapter reviews traditional and scientific approaches to the use of herbal medicine in
treating an array of conditions by system. Clinically, it is common to find more than one …

Antinociceptive Activity of Trichilia catigua Hydroalcoholic Extract: New Evidence on Its Dopaminergic Effects

AF Viana, IS Maciel, EM Motta, PC Leal… - Evidence‐Based …, 2011 - Wiley Online Library
Trichilia catigua is a native plant of Brazil; its barks are used by some local pharmaceutical
companies to prepare tonic drinks, such as Catuama. The present study was addressed to …