The aims of severe perioperative bleeding management are three-fold. First, preoperative
identification by anamesis and laboratory testing of those patients for whom the …

Although rare, the prevalence of inherited platelet function disorders (IPFD) is probably
underestimated due to under‐diagnosis 1. IPFD are heterogeneous in severity, mechanisms …

The management of perioperative bleeding involves multiple assessments and strategies to
ensure appropriate patient care. Initially, it is important to identify those patients with an …

The guideline writing group was selected to be representative of UK‐based medical experts.
MEDLINE was systematically searched for publications in English up to the Summer of 2010 …

The PFA-100 (platelet function analyzer) is a relatively new tool for the investigation of
primary hemostasis. This article reviews the history of the PFA-100 and details its clinical …

Mild inherited bleeding disorders are relatively common in the general population. Despite
recent advances in diagnostic approaches, mild inherited bleeding disorders still pose a …

The “platelet function analyzer”(PFA)− 100 was first introduced to us in 1995. Since then, the
instrument has appeared in over 50 reviews and almost 1000 publications. Recently, the …

Abstract von Willebrand disease is a common inherited bleeding disorder characterized by
excessive mucocutaneous bleeding. Characteristic bleeding symptoms include epistaxis …

Patient Blood Management (PBM) is a holistic approach to the management of blood as a
resource for each, single patient; it is a multimodal strategy that is implemented through the …

Recent studies have demonstrated that only 30% of patients referred for assessment of a
possible bleeding tendency will eventually be diagnosed with a mild bleeding disorder …