An up-to-date review of natural nanoparticles for cancer management

D Ion, AG Niculescu, DN Păduraru, O Andronic… - Pharmaceutics, 2021 - mdpi.com
Cancer represents one of the leading causes of morbidity and mortality worldwide, imposing
an urgent need to develop more efficient treatment alternatives. In this respect, much …

Polymer-based nanosystems—A versatile delivery approach

AG Niculescu, AM Grumezescu - Materials, 2021 - mdpi.com
Polymer-based nanoparticles of tailored size, morphology, and surface properties have
attracted increasing attention as carriers for drugs, biomolecules, and genes. By protecting …

Synthesis and characterization of a novel, pH-responsive sustained release nanocarrier using polyethylene glycol, graphene oxide, and natural silk fibroin protein by …

PA Jeshvaghani, M Pourmadadi, F Yazdian… - International Journal of …, 2023 - Elsevier
In this study, for the first time, by employing a simple and efficient double nano-emulsification
method and using sweet almond oil as the organic phase, polyethylene glycol …

Green synthesized polyvinylpyrrolidone/titanium dioxide hydrogel nanocomposite modified with agarose macromolecules for sustained and pH-responsive release of …

M Pourmadadi, F Yazdian, A Koulivand… - International Journal of …, 2023 - Elsevier
Cancer, as one of the most challenging diseases of the last century, has a significant
number of patients and deaths every year. Various strategies have been explored for the …

Highly-magnetic mineral protein–tannin vehicles with anti-breast cancer activity

PA Demina, AA Abalymov, DV Voronin… - Materials Chemistry …, 2021 - pubs.rsc.org
Anticancer hybrid mineral highly-magnetic protein–tannin vehicles are tunable and
controllable external triggers for drug delivery systems. The saturation level of submicron …

Macromolecular design of pH sensitive, folic acid functionalized double hydrophilic block copolymer nanogels as methotrexate carriers to breast cancer cells

M Ghaffarlou, SD Sütekin, H Hammamchi… - Journal of Drug Delivery …, 2023 - Elsevier
Abstract Poly (acrylic acid)-poly (vinyl amine) block copolymer nanogels were produced for
the first time by a simple and environmentally friendly irradiation method. To enhance …

Tumor cell capture using platelet-based and platelet-mimicking modified human serum albumin submicron particles

X Zhao, R Georgieva, P Rerkshanandana… - International Journal of …, 2022 - mdpi.com
The co-localization of platelets and tumor cells in hematogenous metastases has long been
recognized. Interactions between platelets and circulating tumor cells (CTCs) contribute to …

Protein-Decorated Microbubbles for Ultrasound-Mediated Cell Surface Manipulation

VA Brans, MD Gray, E Sezgin… - ACS Applied Bio …, 2023 - ACS Publications
Delivering cargo to the cell membranes of specific cell types in the body is a major challenge
for a range of treatments, including immunotherapy. This study investigates employing …

Human serum albumin nanoparticles as a carrier for on-demand sorafenib delivery

TM Caputo, AM Cusano, M Ruvo… - Current …, 2022 - ingentaconnect.com
Background: Drug delivery systems based on Human Serum Albumin (HSA) have been
widely investigated due to their capability to interact with several molecules together with …

Shape Matters: Impact of Mesoporous Silica Nanoparticle Morphology on Anti-Tumor Efficacy

W Fang, K Yu, S Zhang, L Jiang, H Zheng, Q Huang… - Pharmaceutics, 2024 - mdpi.com
A nanoparticle's shape is a critical determinant of its biological interactions and therapeutic
effectiveness. This study investigates the influence of shape on the performance of …