E-cigarette use causes a unique innate immune response in the lung, involving increased neutrophilic activation and altered mucin secretion

B Reidel, G Radicioni, PW Clapp, AA Ford… - American journal of …, 2018 - atsjournals.org
Rationale: E-cigarettes have become increasingly popular and little is known about their
potential adverse health effects. Objectives: To determine the effects of e-cigarette use on …

[HTML][HTML] Alterations in the sputum proteome and transcriptome in smokers and early-stage COPD subjects

B Titz, A Sewer, T Schneider, A Elamin, F Martin… - Journal of …, 2015 - Elsevier
Chronic obstructive pulmonary disease (COPD) is one of the most prevalent lung diseases.
Cigarette smoking is the main risk factor for COPD. In this parallel-group clinical study we …

A critical assessment of the scientific basis, and implementation, of regulations for the safety assessment and marketing of innovative tobacco-related products

RD Combes, M Balls - Alternatives to Laboratory Animals, 2015 - journals.sagepub.com
Our scientific, logistical, ethical and animal welfare-related concerns about the latest US
Food and Drug Administration (FDA) regulations for existing and so-called 'new'tobacco …

[HTML][HTML] The role of plasma microseminoprotein-beta in prostate cancer: an observational nested case–control and Mendelian randomization study in the European …

KS Byrne, PN Appleby, TJ Key, MV Holmes… - Annals of …, 2019 - Elsevier
ABSTRACT Background Microseminoprotein-beta (MSP), a protein secreted by the prostate
epithelium, may have a protective role in the development of prostate cancer. The only …

Lifestyle, biochemical, and genetic risk factors for prostate cancer

K Byrne - 2017 - ora.ox.ac.uk
Despite considerable research there are no established risk factors for prostate cancer
beyond age, family history, ethnicity, genetic factors, and insulin-like growth factor I …