Decellularization techniques for tissue engineering: towards replicating native extracellular matrix architecture in liver regeneration

I Allu, AK Sahi, M Koppadi, S Gundu… - Journal of Functional …, 2023 - mdpi.com
The process of tissue regeneration requires the utilization of a scaffold, which serves as a
structural framework facilitating cellular adhesion, proliferation, and migration within a …

Biomedical application of decellularized scaffolds

F Zhang, H Gao, X Jiang, F Yang, J Zhang… - ACS Applied Bio …, 2023 - ACS Publications
Tissue loss and end-stage organ failure are serious health problems across the world.
Natural and synthetic polymer scaffold material based artificial organs play an important role …

Multi-step extracellular matrix remodelling and stiffening in the development of idiopathic pulmonary fibrosis

C Júnior, A Ulldemolins, M Narciso… - International Journal of …, 2023 - mdpi.com
The extracellular matrix (ECM) of the lung is a filamentous network composed mainly of
collagens, elastin, and proteoglycans that provides structural and physical support to its …

Detergent-based decellularization for anisotropic cardiac-specific extracellular matrix scaffold generation

TA Chen, D Sharma, W Jia, D Ha, K Man, J Zhang… - Biomimetics, 2023 - mdpi.com
Cell-derived extracellular matrix (ECM) has become increasingly popular in tissue
engineering applications due to its ability to provide tailored signals for desirable cellular …

A novel allogeneic acellular matrix scaffold for porcine cartilage regeneration

H Jiang, J Lu, J Li, Z Liu, F Chen, R Wu, X Xu, Y Liu… - BMC …, 2023 - Springer
Background Cartilage defects are common sports injuries without significant treatment.
Articular cartilage with inferior regenerative potential resulted in the poor formation of …

Characterization and biocompatibility evaluation of acellular rat skin scaffolds for skin tissue engineering applications

LT Momen, A Abdolmaleki, A Asadi, S Zahri - Cell and Tissue Banking, 2024 - Springer
Utilization of acellular scaffolds, extracellular matrix (ECM) without cell content, is growing in
tissue engineering, due to their high biocompatibility, bioactivity ad mechanical support …

Lung micrometastases display ECM depletion and softening while macrometastases are 30-fold stiffer and enriched in fibronectin

M Narciso, Á Martínez, C Júnior, N Díaz-Valdivia… - Cancers, 2023 - mdpi.com
Simple Summary This study examined the mechanical properties of the extracellular matrix
(ECM) in lung metastases from two cancer models: lung carcinoma and melanoma. The …

Effect of decellularization using sodium dodecyl sulfate on glycosaminoglycans content in the liver

M Kasturi, KS Vasanthan - Regenerative medicine, 2023 - Taylor & Francis
For the last decade, 3D bioprinting has been being explored for the in vitro fabrication of
tissues and organs. Various bioinks are being formulated and researched for 3D bioprinting …

Decellularization of Dense Regular Connective Tissue—Cellular and Molecular Modification with Applications in Regenerative Medicine

K Data, M Kulus, H Ziemak, M Chwarzyński… - Cells, 2023 - mdpi.com
Healing of dense regular connective tissue, due to a high fiber-to-cell ratio and low
metabolic activity and regeneration potential, frequently requires surgical implantation or …

A novel approach for the endothelialization of xenogeneic decellularized vascular tissues by human cells utilizing surface modification and dynamic culture

WJ Ho, M Kobayashi, K Murata, Y Hashimoto… - Scientific Reports, 2022 - nature.com
Decellularized xenogeneic vascular grafts can be used in revascularization surgeries. We
have developed decellularization methods using high hydrostatic pressure (HHP), which …