Biology of classical Hodgkin lymphoma: implications for prognosis and novel therapies
A Mottok, C Steidl - Blood, The Journal of the American Society …, 2018 - ashpublications.org
Hodgkin lymphoma is considered a prime example of treatment success, with cure rates
exceeding 80% using modern combined modality therapies. However, especially in …
exceeding 80% using modern combined modality therapies. However, especially in …
Genomic profiling for clinical decision making in lymphoid neoplasms
L De Leval, AA Alizadeh, PL Bergsagel… - Blood, The Journal …, 2022 - ashpublications.org
With the introduction of large-scale molecular profiling methods and high-throughput
sequencing technologies, the genomic features of most lymphoid neoplasms have been …
sequencing technologies, the genomic features of most lymphoid neoplasms have been …
Single-cell transcriptome analysis reveals disease-defining T-cell subsets in the tumor microenvironment of classic Hodgkin lymphoma
T Aoki, LC Chong, K Takata, K Milne, M Hav… - Cancer discovery, 2020 - AACR
Hodgkin lymphoma is characterized by an extensively dominant tumor microenvironment
(TME) composed of different types of noncancerous immune cells with rare malignant cells …
(TME) composed of different types of noncancerous immune cells with rare malignant cells …
Tumor and microenvironment response but no cytotoxic T-cell activation in classic Hodgkin lymphoma treated with anti-PD1
S Reinke, PJ Bröckelmann, I Iaccarino… - Blood, The Journal …, 2020 - ashpublications.org
Classic Hodgkin lymphoma (cHL) is the cancer type most susceptible to antibodies targeting
programmed cell death protein 1 (PD1) and is characterized by scarce Hodgkin and Reed …
programmed cell death protein 1 (PD1) and is characterized by scarce Hodgkin and Reed …
Single-cell profiling reveals the importance of CXCL13/CXCR5 axis biology in lymphocyte-rich classic Hodgkin lymphoma
T Aoki, LC Chong, K Takata, K Milne… - Proceedings of the …, 2021 - National Acad Sciences
Lymphocyte-rich classic Hodgkin lymphoma (LR-CHL) is a rare subtype of Hodgkin
lymphoma. Recent technical advances have allowed for the characterization of specific …
lymphoma. Recent technical advances have allowed for the characterization of specific …
Pembrolizumab plus vorinostat induces responses in patients with Hodgkin lymphoma refractory to prior PD-1 blockade
M Mei, L Chen, J Godfrey, J Song, C Egelston… - Blood, 2023 - ashpublications.org
This phase 1 study evaluated the addition of vorinostat to pembrolizumab in patients with
relapsed/refractory (RR) classical Hodgkin lymphoma (cHL), diffuse large B-cell lymphoma …
relapsed/refractory (RR) classical Hodgkin lymphoma (cHL), diffuse large B-cell lymphoma …
Gene expression profiling of gray zone lymphoma
C Sarkozy, L Chong, K Takata, EA Chavez… - Blood …, 2020 - ashpublications.org
Gray zone lymphoma (GZL), a B-cell lymphoma with features intermediate between large B-
cell lymphoma (LBCL) and classic Hodgkin lymphoma (cHL), is a rare and poorly defined …
cell lymphoma (LBCL) and classic Hodgkin lymphoma (cHL), is a rare and poorly defined …
Spatially resolved tumor microenvironment predicts treatment outcomes in relapsed/refractory Hodgkin lymphoma
PURPOSE About a third of patients with relapsed or refractory classic Hodgkin lymphoma
(r/r CHL) succumb to their disease after high-dose chemotherapy followed by autologous …
(r/r CHL) succumb to their disease after high-dose chemotherapy followed by autologous …
Hodgkin lymphoma: a special microenvironment
G Opinto, C Agostinelli, S Ciavarella, A Guarini… - Journal of Clinical …, 2021 - mdpi.com
Classical Hodgkin's lymphoma (cHL) is one of the most particular lymphomas for the few
tumor cells surrounded by an inflammatory microenvironment. Reed-Sternberg (RS) and …
tumor cells surrounded by an inflammatory microenvironment. Reed-Sternberg (RS) and …