Advancing plant biology through deep learning-powered natural language processing

S Peng, L Rajjou - Plant Cell Reports, 2024 - Springer
The application of deep learning methods, specifically the utilization of Large Language
Models (LLMs), in the field of plant biology holds significant promise for generating novel …

Integrating transformer-based machine learning with SERS technology for the analysis of hazardous pesticides in spinach

M Hajikhani, A Hegde, J Snyder, J Cheng… - Journal of Hazardous …, 2024 - Elsevier
This study introduces an innovative strategy for the rapid and accurate identification of
pesticide residues in agricultural products by combining surface-enhanced Raman …

Enhancing antibody language models with structural information

J Barton, JD Galson, J Leem - bioRxiv, 2024 - biorxiv.org
The central tenet of molecular biology is that a protein's amino acid sequence determines its
three-dimensional structure, and thus its function. However, proteins with similar sequences …

Zero-shot prediction of mutation effects with multimodal deep representation learning guides protein engineering

P Cheng, C Mao, J Tang, S Yang, Y Cheng, W Wang… - Cell Research, 2024 - nature.com
Mutations in amino acid sequences can provoke changes in protein function. Accurate and
unsupervised prediction of mutation effects is critical in biotechnology and biomedicine, but …

Pepharmony: A multi-view contrastive learning framework for integrated sequence and structure-based peptide encoding

R Zhang, H Wu, C Liu, H Li, Y Wu, K Li, Y Wang… - arXiv preprint arXiv …, 2024 - arxiv.org
Recent advances in protein language models have catalyzed significant progress in peptide
sequence representation. Despite extensive exploration in this field, pre-trained models …

[PDF][PDF] Jointly Embedding Protein Structures and Sequences through Residue Level Alignment

F Birnbaum, S Jain, A Madry, AE Keating - Machine Learning for Structural …, 2023 - mlsb.io
The relationships between protein sequences, structures, and their functions are determined
by complex codes that scientists aim to decipher. While structures contain key information …

Large protein databases reveal structural complementarity and functional locality

P Szczerbiak, L Szydlowski, W Wydmanski… - bioRxiv, 2024 - biorxiv.org
Recent breakthroughs in protein structure prediction have led to an unprecedented surge in
high-quality 3D models, highlighting the need for efficient computational solutions to …

Prot2Token: A multi-task framework for protein language processing using autoregressive language modeling

M Pourmirzaei, F Esmaili, M Pourmirzaei, D Wang… - bioRxiv, 2024 - biorxiv.org
This paper proposes a versatile tokenization method and introduces Prot2Token, a model
that combines autoregressive language modeling with protein language models (PLMs) to …