[HTML][HTML] Hallmarks of regeneration

KD Poss, EM Tanaka - Cell stem cell, 2024 - cell.com
Regeneration is a heroic biological process that restores tissue architecture and function in
the face of day-to-day cell loss or the aftershock of injury. Capacities and mechanisms for …

Advanced gene nanocarriers/scaffolds in nonviral-mediated delivery system for tissue regeneration and repair

W Zhang, Y Hou, S Yin, Q Miao, K Lee, X Zhou… - Journal of …, 2024 - Springer
Tissue regeneration technology has been rapidly developed and widely applied in tissue
engineering and repair. Compared with traditional approaches like surgical treatment, the …

Spinal cord repair is modulated by the neurogenic factor Hb-egf under direction of a regeneration-associated enhancer

V Cigliola, A Shoffner, N Lee, J Ou, TJ Gonzalez… - Nature …, 2023 - nature.com
Unlike adult mammals, zebrafish regenerate spinal cord tissue and recover locomotor ability
after a paralyzing injury. Here, we find that ependymal cells in zebrafish spinal cords …

Emerging frontiers in regenerative medicine

KL McKinley, MT Longaker, S Naik - Science, 2023 - science.org
Nearly every human malady, be it injury, infection, chronic disease, or degenerative disease,
damages tissues. Moreover, 45% of all deaths can be traced to inflammation-and fibrosis …

An injury-responsive mmp14b enhancer is required for heart regeneration

I Zlatanova, F Sun, RS Wu, X Chen, BH Lau… - Science …, 2023 - science.org
Mammals have limited capacity for heart regeneration, whereas zebrafish have
extraordinary regeneration abilities. During zebrafish heart regeneration, endothelial cells …

Runt-related transcription factors and gene regulatory mechanisms in skeletal development and diseases

H Hojo, S Ohba - Current Osteoporosis Reports, 2023 - Springer
Abstract Purpose of Review Runt-related transcription factors (RUNX) play critical roles in
skeletal development, metabolism, and diseases. In mammals, three RUNX members …

Regeneration or scarring derive from specific evolutionary environmental adaptations of the life cycles in different animals

L Alibardi - Biology, 2023 - mdpi.com
Simple Summary The present MS proposes a new hypothesis that motivates why only some
animals can regenerate their organs. This derives from their simple body constitution …

Mesenchymal stem cells in soft tissue regenerative medicine: a comprehensive review

A Rehman, A Nigam, L Laino, D Russo, C Todisco… - Medicina, 2023 - mdpi.com
Soft tissue regeneration holds significant promise for addressing various clinical challenges,
ranging from craniofacial and oral tissue defects to blood vessels, muscle, and fibrous tissue …

Enduring questions in regenerative biology and the search for answers

AW Seifert, EM Duncan, RM Zayas - Communications Biology, 2023 - nature.com
The potential for basic research to uncover the inner workings of regenerative processes
and produce meaningful medical therapies has inspired scientists, clinicians, and patients …

Emerging RUNX2-mediated gene regulatory mechanisms consisting of multi-layered regulatory networks in skeletal development

H Hojo - International Journal of Molecular Sciences, 2023 - mdpi.com
Skeletal development is tightly coordinated by chondrocytes and osteoblasts, which are
derived from skeletal progenitors, and distinct cell-type gene regulatory programs underlie …