Glioblastoma multiforme: a multi-omics analysis of driver genes and tumour heterogeneity

GE Herrera-Oropeza, C Angulo-Rojo… - Interface …, 2021 - royalsocietypublishing.org
Glioblastoma (GBM) is the most aggressive and common brain cancer in adults with the
lowest life expectancy. The current neuro-oncology practice has incorporated genes …

A new mathematical model for controlling tumor growth based on microenvironment acidity and oxygen concentration

F Pourhasanzade… - BioMed Research …, 2021 - Wiley Online Library
Hypoxia and the pH level of the tumor microenvironment have a great impact on the
treatment of tumors. Here, the tumor growth is controlled by regulating the oxygen …

A multiscale model of the role of microenvironmental factors in cell segregation and heterogeneity in breast cancer development

JR Romero-Arias, CA González-Castro… - PLOS Computational …, 2023 - journals.plos.org
We analyzed a quantitative multiscale model that describes the epigenetic dynamics during
the growth and evolution of an avascular tumor. A gene regulatory network (GRN) formed by …

Invasiveness of a Growth-Migration System in a Two-dimensional Percolation cluster: A Stochastic Mathematical Approach

R Yang, C Jiang, Y Shao - Bulletin of Mathematical Biology, 2022 - Springer
We developed a framework based on the software Unstructured Reaction-Diffusion Master
Equation (URDME) to address tumor cells' proliferation and migration in a heterogeneous …

Maximizing circular tiles on fractals: A first step to optimization in fractals

C García-Miguel, J San Martín - Fractals, 2021 - World Scientific
Fractal covering with non-overlapping circular tiles follows a power law, when the circular
tiles cover a preset mass of the fractal and their centers are chosen randomly and …

Invasiveness of Cancer Populations in a Two-dimensional Percolation cluster: a Stochastic Mathematical Approach

R Yang, Y Shao, C Jiang - bioRxiv, 2022 - biorxiv.org
A framework for the software Unstructured Reaction-Diffusion Master Equation (URDME)
was developed. A mitogenic paracrine signaling pathway was introduced …

Microenvironmental factors in cell segregation and heterogeneity in breast cancer development

JR Romero-Arias, CA González-Castro… - bioRxiv, 2021 - biorxiv.org
We analyzed a quantitative model that describes the epigenetic dynamics during the growth
and evolution of an avascular tumor. A gene regulatory network (GRN) formed by a set of ten …

Optimización en fractales

MC García-Miguel Fernández - 2022 - oa.upm.es
En esta tesis buscamos cuál es la distribución de las teselas distribuidas aleatoriamente
sobre un fractal, ya sea que las teselas sean de radio fjo o contengan una masa dada del …

Glioblastoma multiforme: a meta-analysis of driver genes, current diagnosis, and tumor heterogeneity

GE Herrera-Oropeza, C Angulo-Rojo… - medRxiv, 2020 - medrxiv.org
Glioblastoma (GBM) is the most aggressive and common brain cancer in adults with the
lowest life expectancy. The current neuro-oncology practice has incorporated genes …

[PDF][PDF] Research Article A New Mathematical Model for Controlling Tumor Growth Based on Microenvironment Acidity and Oxygen Concentration

F Pourhasanzade, SH Sabzpoushan - 2021 - academia.edu
Hypoxia and the pH level of the tumor microenvironment have a great impact on the
treatment of tumors. Here, the tumor growth is controlled by regulating the oxygen …