Circulating tumor cells in breast cancer: detection systems, molecular characterization, and future challenges

ES Lianidou, A Markou - Clinical chemistry, 2011 - academic.oup.com
BACKGROUND Circulating tumor cell (CTC) analysis is a promising new diagnostic field for
estimating the risk for metastatic relapse and metastatic progression in patients with cancer …

[HTML][HTML] CTC enumeration and characterization: moving toward personalized medicine

A Toss, Z Mu, S Fernandez… - Annals of translational …, 2014 - ncbi.nlm.nih.gov
The primary cause of tumor-related death in breast cancer (BC) is still represented by distant
metastasization. The dissemination of tumor cells from the primary tumor to distant sites …

[HTML][HTML] Antioxidant, anti-inflammatory and neuroprotective effect of kaempferol on rotenone-induced Parkinson's disease model of rats and SH-S5Y5 cells by …

X Pan, X Liu, H Zhao, B Wu, G Liu - Journal of Functional Foods, 2020 - Elsevier
The present study investigated the antioxidant and neuroprotective effect of kaempferol
against rotenone-induced Parkinson's disease (PD). Kaempferol inhibits apomorphine …

Filter‐based isolation, enrichment, and characterization of circulating tumor cells

S Khetani, M Mohammadi… - Biotechnology and …, 2018 - Wiley Online Library
Isolation of circulating tumor cells (CTCs) from blood has long been a challenge due to the
rarity and heterogeneity of these cells. Detection technologies have predominantly focused …

Mangiferin exert cardioprotective and anti-apoptotic effects in heart failure induced rats

T Jiang, F Han, G Gao, M Liu - Life sciences, 2020 - Elsevier
Mangiferin is a well-known xanthone extracted from mango leaves (Mangifera indica Linn).
Mangiferin is widely distributed in the bark, peel, leaf, seed, stalk, and kernel of mango and …

Clinical outcome with correlation to disseminated tumor cell (DTC) status after DTC-guided secondary adjuvant treatment with docetaxel in early breast cancer

B Naume, M Synnestvedt, RS Falk… - Journal of Clinical …, 2014 - ascopubs.org
Purpose The presence of disseminated tumor cells (DTCs) in bone marrow (BM) predicts
survival in early breast cancer. This study explores the use of DTCs for identification of …

[HTML][HTML] Curcumin attenuates cerebral ischemia injury in Sprague–Dawley rats and PC12 cells by suppressing overactivated autophagy

Y Zhang, M Fang, Y Sun, T Zhang, N Shi, J Li… - … of Photochemistry and …, 2018 - Elsevier
The present study assessed whether the protective effects of curcumin against cerebral
ischemia injury were due to the suppression of overactivated autophagy. Curcumin is a well …

Circulating tumor cells and circulating tumor DNA

E Lianidou, D Hoon - Principles and applications of molecular diagnostics, 2018 - Elsevier
Background Classic tissue biopsies or surgical resections are invasive procedures that
capture only a single snapshot in the evolution of cancer. In contrast, a blood-based test or …

[HTML][HTML] Fangchinoline supplementation attenuates inflammatory markers in experimental rheumatoid arthritis-induced rats

L Shan, L Tong, L Hang, H Fan - Biomedicine & Pharmacotherapy, 2019 - Elsevier
The present study evaluated the anti-inflammatory activity of fangchinoline in rheumatoid
arthritis-induced rats. Rats were grouped into sham (group I), rheumatoid arthritis (group II …

Chronic oxidative stress promotes molecular changes associated with epithelial mesenchymal transition, NRF2, and breast cancer stem cell phenotype

A Čipak Gašparović, L Milković, N Dandachi, S Stanzer… - Antioxidants, 2019 - mdpi.com
Oxidative stress plays a role in carcinogenesis, but it also contributes to the modulation of
tumor cells and microenvironment caused by chemotherapeutics. One of the consequences …