Mycobacteria activate a series of macrophage signalling pathways upon engaging host cell
receptors and during the invasion process. These signals initiate a cascade of events …

There are over 170 known species and subspecies of mycobacteria that have been
identified, and new species continue to be discovered (http://www. bacterio …

After internalization into macrophages non‐pathogenic mycobacteria are killed within
phagosomes. Pathogenic mycobacteria can block phagosome maturation and grow inside …

Infections contribute to carcinogenesis through inflammation-related mechanisms. H. pylori
infection is a significant risk factor for gastric carcinogenesis. However, the molecular …

The role of mitogen-activated protein kinase (MAPK) pathways in the secretion of tumor
necrosis factor (TNF)-α, interleukin (IL)-10, IL-8, and monocyte chemotactic protein-1 (MCP …

Tissue factor (TF) is the primary initiator of coagulation, and the TF pathway mediates
signaling through protease-activated receptors (PARs). In sepsis, TF is up-regulated as part …

Pathogenic mycobacteria are highly adapted for survival within host mononuclear
phagocytes. This is largely due to the organism's capacity to prevent macrophage activation …

Understanding how pathogenic mycobacteria subvert the protective immune response is
crucial to the development of strategies aimed at controlling mycobacterial infections …

Mycobacterium avium is an opportunistic pathogen that commonly infects individuals
colonized with HIV-1, although it is less frequent in the post-HAART era. These …

We investigated the role of cell signaling through the mitogen-activated protein kinase-p38
(MAPKp38) pathway on the antimicrobial functions and cytokine expression by bovine …