Nanomedicine-based strategies to improve treatment of cutaneous leishmaniasis

N Goonoo, MA Laetitia Huët… - Royal Society …, 2022 - royalsocietypublishing.org
Nanomedicine strategies were first adapted and successfully translated to clinical
application for diseases, such as cancer and diabetes. These strategies would no doubt …

The binomial parasite-host immunity in the healing process and in reactivation of human tegumentary leishmaniasis

F Conceição-Silva, J Leite-Silva… - Frontiers in …, 2018 - frontiersin.org
Leishmaniasis is a vector-borne infectious disease caused by different species of protozoa
from the Leishmania genus. Classically, the disease can be classified into two main clinical …

Prospects of essential oils in controlling pathogenic biofilm

H Jafri, FA Ansari, I Ahmad - New look to phytomedicine, 2019 - Elsevier
The transition from planktonic to sessile mode of bacterial growth facilitates the survival in
diverse environmental niches. Majority of bacterial infections involve biofilm formation …

Distinct microbiome profiles and biofilms in Leishmania donovani-driven cutaneous leishmaniasis wounds

TD Jayasena Kaluarachchi, PM Campbell… - Scientific reports, 2021 - nature.com
The endemic strain of Leishmania donovani in Sri Lanka causes cutaneous leishmaniasis
(CL) rather than more common visceral form. We have visualized biofilms and profiled the …

An old drug and different ways to treat cutaneous leishmaniasis: intralesional and intramuscular meglumine antimoniate in a reference center, Rio de Janeiro, Brazil

C Oliveira-Ribeiro, MIF Pimentel… - PLoS Neglected …, 2021 - journals.plos.org
Background Treatment of cutaneous leishmaniasis (CL) remains challenging since the
drugs currently used are quite toxic, thus contributing to lethality unrelated to the disease …

Treating leishmaniasis in Amazonia, part 2: Multi-target evaluation of widely used plants to understand medicinal practices

E Houël, M Ginouves, N Azas, E Bourreau… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Leishmaniasis are widely distributed among tropical and
subtropical countries, and remains a crucial health issue in Amazonia. Indigenous groups …

Lignin–cellulose complexes derived from agricultural wastes for combined antibacterial and tissue engineering scaffolds for cutaneous leishmaniasis wounds

MAL Huët, IC Phul, N Goonoo, Z Li, X Li… - Journal of Materials …, 2024 - pubs.rsc.org
Bacterial infections in wounds significantly impair the healing process. The use of natural
antibacterial products over synthetic antibiotics has emerged as a new trend to address …

Prokaryotic and eukaryotic skin microbiota modifications triggered by Leishmania infection in localized Cutaneous Leishmaniasis

J Jaimes, LH Patiño, G Herrera, C Cruz… - PLOS Neglected …, 2024 - journals.plos.org
Cutaneous Leishmaniasis (CL) is a tropical disease characterized by cutaneous ulcers,
sometimes with satellite lesions and nodular lymphangitis. Leishmania parasites …

The designing of a gel formulation with chitosan polymer using liposomes as nanocarriers of amphotericin B for a non-invasive treatment model of cutaneous …

N GÜRBÜZ ÇOLAK, EÖ ÇETİN UYANIKGİL, Y Özbel… - Acta Parasitologica, 2022 - Springer
Purpose Leishmaniasis is a disease caused by different Leishmania spp., which are
transmitted to humans by a bite of infected female sand flies. Cutaneous leishmaniasis (CL …

Possible clinical implications and future directions of managing bacterial biofilms in cutaneous leishmaniasis wounds

TDJ Kaluarachchi, PM Campbell… - Tropical Medicine and …, 2022 - Springer
Cutaneous leishmaniasis (CL) lesions are chronic and result in disfiguring scars. The
microbiological aspects of these wounds have not been systematically investigated. We …