Streptococcus pneumoniae epidemiology, pathogenesis and control
AR Narciso, R Dookie, P Nannapaneni… - Nature Reviews …, 2024 - nature.com
Infections caused by Streptococcus pneumoniae (also known as pneumococci) pose a
threat to human health. Pneumococcal infections are the most common cause of milder …
threat to human health. Pneumococcal infections are the most common cause of milder …
Pilus of Streptococcus pneumoniae: structure, function and vaccine potential
C Miao, Y Cui, Z Yan, Y Jiang - Frontiers in Cellular and Infection …, 2023 - frontiersin.org
The pilus is an extracellular structural part that can be detected in some Streptococcus
pneumoniae (S. pneumoniae) isolates (type I pili are found in approximately 30% of strains …
pneumoniae (S. pneumoniae) isolates (type I pili are found in approximately 30% of strains …
StkP-and PhpP-mediated posttranslational modifications modulate the S. pneumoniae metabolism, polysaccharide capsule, and virulence
S Kant, Y Sun, V Pancholi - Infection and immunity, 2023 - Am Soc Microbiol
ABSTRACT Pneumococcal Ser/Thr kinase (StkP) and its cognate phosphatase (PhpP) play
a crucial role in bacterial cytokinesis. However, their individual and reciprocal metabolic and …
a crucial role in bacterial cytokinesis. However, their individual and reciprocal metabolic and …
Conserved molecular chaperone PrsA stimulates protective immunity against group A Streptococcus
CY Lai, JX Xie, MC Lai, ZY Wu, JS Lin, YT Huang… - npj Vaccines, 2024 - nature.com
Abstract Group A Streptococcus (GAS) is a significant human pathogen that poses a global
health concern. However, the development of a GAS vaccine has been challenging due to …
health concern. However, the development of a GAS vaccine has been challenging due to …
Intracellular survival of Streptococcus pneumoniae in human alveolar macrophages is augmented with HIV infection
People Living with HIV (PLHIV) are at an increased risk of pneumococcal pneumonia than
HIV-uninfected adults, but the reasons for this are still not well understood. We investigated …
HIV-uninfected adults, but the reasons for this are still not well understood. We investigated …
Effect of Iron Limitation, Elevated Temperature, and Florfenicol on the Proteome and Vesiculation of the Fish Pathogen Aeromonas salmonicida
We analyzed the proteomic response of the Gram-negative fish pathogen A. salmonicida to
iron limitation, an elevated incubation temperature, and the antibiotic florfenicol. Proteins …
iron limitation, an elevated incubation temperature, and the antibiotic florfenicol. Proteins …
Lipidation of pneumococcal proteins enables activation of human antigen-presenting cells and initiation of an adaptive immune response
AD Paulikat, D Schwudke, S Hammerschmidt… - Frontiers in …, 2024 - frontiersin.org
Streptococcus pneumoniae remains a significant global threat, with existing vaccines having
important limitations such as restricted serotype coverage and high manufacturing costs …
important limitations such as restricted serotype coverage and high manufacturing costs …
The role of pneumococcal extracellular vesicles on the pathophysiology of the kidney disease hemolytic uremic syndrome
M Battista, B Hoffmann, Y Bachelot, L Zimmermann… - Msphere, 2023 - Am Soc Microbiol
Streptococcus pneumoniae-induced hemolytic uremic syndrome (Sp-HUS) is a kidney
disease characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute …
disease characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute …
Biological puzzles solved by using Streptococcus pneumoniae: a historical review of the pneumococcal studies that have impacted medicine and shaped molecular …
NL Hiller, CJ Orihuela - Journal of Bacteriology, 2024 - Am Soc Microbiol
The major human pathogen Streptococcus pneumoniae has been the subject of intensive
clinical and basic scientific study for over 140 years. In multiple instances, these efforts have …
clinical and basic scientific study for over 140 years. In multiple instances, these efforts have …
Mucosal adjuvanticity and mucosal booster effect of colibactin-depleted probiotic Escherichia coli membrane vesicles
H Uchiyama, T Kudo, T Yamaguchi… - Human Vaccines & …, 2024 - Taylor & Francis
There is a growing interest in development of novel vaccines against respiratory tract
infections, due to COVID-19 pandemic. Here, we examined mucosal adjuvanticity and the …
infections, due to COVID-19 pandemic. Here, we examined mucosal adjuvanticity and the …