Sodium/glucose cotransporter 2 (SGLT2) inhibitors exert important renoprotective effects in
the diabetic kidney, which cannot be readily explained by their actions to lower blood …

Obesity poses a severe threat to human health, including the increased prevalence of
hypertension, insulin resistance, diabetes mellitus, cancer, inflammation, sleep apnoea and …

The development of sodium-glucose transporter 2 inhibitor (SGLT2i) broadens the
therapeutic strategies in treating diabetes mellitus. By inhibiting sodium and glucose …

Hypoxia-inducible factor-1α (HIF-1α) is a primary metabolic sensor, and is expressed in
different immune cells, such as macrophage, dendritic cell, neutrophil, T cell, and non …

Abstract Sodium-glucose co-transporter 2 (SGLT2) inhibitors reduce the risk of serious heart
failure events, even though SGLT2 is not expressed in the myocardium. This …

Endothelial cell dysfunction and diabetic vascular complications are intrinsically linked.
Although BDNF plays a protective role in cerebral microvascular complications caused by …

Highlights•The vicious cycle of diabetic liver injury.•Elevated levels of plasma Free Fatty Acid
play a key role in the pathogenesis of diabetes.•Insulin resistance causes hyperglycemia …

In recent years, inhibitors of the sodium-glucose co-transporter 2 (SGLT2 inhibitors) have
been shown to have significant protective effects on the kidney and the cardiovascular …

This study first systematically analyzed the constituents of an albino mutant strain of
Auricularia cornea (AU). After 8 weeks of continuous treatment with metformin (Met)(0.1 …

Abstract Allium Sativum L.(ASL) extract is one of the medicinal and aromatic products used
in pharmaceutical, food, cosmetic and perfumery industries. The scientific literature …