MIF-dependent control of tumor immunity

JT Noe, RA Mitchell - Frontiers in immunology, 2020 - frontiersin.org
Initially identified as a T lymphocyte-elicited inhibitor of macrophage motility, macrophage
migration inhibitory factor (MIF) has since been found to be expressed by nearly every …

The Th17/Treg cell balance: a gut microbiota-modulated story

H Cheng, X Guan, D Chen, W Ma - Microorganisms, 2019 - mdpi.com
The intestinal tract of vertebrates is normally colonized with a remarkable number of
commensal microorganisms that are collectively referred to as gut microbiota. Gut microbiota …

The role of Th17 cells in the pathogenesis and treatment of breast cancer

V Karpisheh, M Ahmadi, K Abbaszadeh-Goudarzi… - Cancer Cell …, 2022 - Springer
Breast cancer is a severe problem worldwide due to an increase in mortality and prevalence
among women. Despite early diagnostic procedures as well as advanced therapies, more …

CD4+ T cells in antitumor immunity

E Montauti, DY Oh, L Fong - Trends in cancer, 2024 - cell.com
Advances in cancer immunotherapy have transformed cancer care and realized
unprecedented responses in many patients. The growing arsenal of novel therapeutics …

[HTML][HTML] Relationship between Th17 immune response and cancer

HS Marques, BB de Brito, FAF da Silva… - World Journal of …, 2021 - ncbi.nlm.nih.gov
Cancer is the second leading cause of death worldwide and epidemiological projections
predict growing cancer mortality rates in the next decades. Cancer has a close relationship …

Immune microenvironment in different molecular subtypes of ductal breast carcinoma

M Sadeghalvad, HR Mohammadi-Motlagh… - Breast cancer research …, 2021 - Springer
Purpose Ductal breast carcinoma as a heterogeneous disease has different molecular
subtypes associated with clinical prognosis and patients' survival. The role of immune …

Autophagy inhibition in breast cancer cells induces ROS-mediated MIF expression and M1 macrophage polarization

I Cotzomi-Ortega, O Nieto-Yanez, I Juarez-Avelar… - Cellular …, 2021 - Elsevier
Autophagy can function as a survival mechanism for cancer cells and therefore, its inhibition
is currently being explored as a therapy for different cancer types. For breast cancer, triple …

MIF is a 3'flap nuclease that facilitates DNA replication and promotes tumor growth

Y Wang, Y Chen, C Wang, M Yang, Y Wang… - Nature …, 2021 - nature.com
How cancer cells cope with high levels of replication stress during rapid proliferation is
currently unclear. Here, we show that macrophage migration inhibitory factor (MIF) is a 3'flap …

The ability of AhR ligands to attenuate delayed type hypersensitivity reaction is associated with alterations in the gut microbiota

OA Abdulla, W Neamah, M Sultan… - Frontiers in …, 2021 - frontiersin.org
Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that regulates T cell
function. The aim of this study was to investigate the effects of AhR ligands, 2, 3, 7, 8 …

Vitamin D, Th17 lymphocytes, and breast cancer

B Filip-Psurska, H Zachary, A Strzykalska, J Wietrzyk - Cancers, 2022 - mdpi.com
Simple Summary The effect of vitamin D3 on the development of breast cancer (favorable,
ineffective, or even unfavorable) depends on many factors, such as age, menopausal status …