Ocular drug delivery: a comprehensive review

S Ahmed, MM Amin, S Sayed - AAPS PharmSciTech, 2023 - Springer
The human eye is a sophisticated organ with distinctive anatomy and physiology that
hinders the passage of drugs into targeted ophthalmic sites. Effective topical administration …

Nano-based eye drop: Topical and noninvasive therapy for ocular diseases

C Wang, Y Pang - Advanced drug delivery reviews, 2023 - Elsevier
Eye drops are the most accessible therapy for ocular diseases, while inevitably suffering
from their lower bioavailability which highly restricts the treatment efficacy. The introduction …

Functional supramolecular systems: Design and applications

IS Antipin, MV Alfimov, VV Arslanov… - Russian Chemical …, 2021 - iopscience.iop.org
The interest in functional supramolecular systems for the design of innovative materials and
technologies, able to fundamentally change the world, is growing at a high pace. The huge …

Multiple roles of chitosan in mucosal drug delivery: an updated review

P Mura, F Maestrelli, M Cirri, N Mennini - Marine Drugs, 2022 - mdpi.com
Chitosan (CS) is a linear polysaccharide obtained by the deacetylation of chitin, which, after
cellulose, is the second biopolymer most abundant in nature, being the primary component …

Chitosan and its derivatives for ocular delivery formulations: Recent advances and developments

A Zamboulis, S Nanaki, G Michailidou, I Koumentakou… - Polymers, 2020 - mdpi.com
Chitosan (CS) is a hemi-synthetic cationic linear polysaccharide produced by the
deacetylation of chitin. CS is non-toxic, highly biocompatible, and biodegradable, and it has …

Developments in Emerging Topical Drug Delivery Systems for Ocular Disorders

S Mandal, P Vishvakarma… - Current Drug Research …, 2024 - benthamdirect.com
According to the current information, using nano gels in the eyes have therapeutic benefits.
Industry growth in the pharmaceutical and healthcare sectors has been filled by …

Nanogels as drug-delivery systems: A comprehensive overview

M Suhail, JM Rosenholm, MU Minhas… - Therapeutic …, 2019 - Taylor & Francis
Nanogels have attracted considerable attention as nanoscopic drug carriers, particularly for
site-specific or time-controlled delivery of bioactive mediators. A high diversity of polymer …

Recent biomedical approaches for chitosan based materials as drug delivery nanocarriers

AT Iacob, FG Lupascu, M Apotrosoaei, IM Vasincu… - Pharmaceutics, 2021 - mdpi.com
In recent decades, drug delivery systems (DDSs) based on nanotechnology have been
attracting substantial interest in the pharmaceutical field, especially those developed based …

Development of acetazolamide loaded bilosomes for improved ocular delivery: Preparation, characterization and in vivo evaluation

AM Mohsen, A Salama, AA Kassem - Journal of Drug Delivery Science and …, 2020 - Elsevier
Acetazolamide (ACZ), a carbonic anhydrase inhibitor, is employed to decrease the
intraocular pressure (IOP) in glaucoma patients. ACZ is characterized by low aqueous …

Chitosan-Based Hydrogel for the Dual Delivery of Antimicrobial Agents Against Bacterial Methicillin-Resistant Staphylococcus aureus Biofilm-Infected Wounds

VO Fasiku, CA Omolo, N Devnarain, UH Ibrahim… - ACS …, 2021 - ACS Publications
Chronic wound infections caused by antibiotic-resistant bacteria have become a global
health concern. This is attributed to the biofilm-forming ability of bacteria on wound surfaces …