Schizophrenia is primed for an increased expression of depression through activation of immuno-inflammatory, oxidative and nitrosative stress, and tryptophan …

G Anderson, M Maes, M Berk - Progress in Neuro-Psychopharmacology …, 2013 - Elsevier
Schizophrenia and depression are two common and debilitating psychiatric conditions. Up
to 61% of schizophrenic patients have comorbid clinical depression, often undiagnosed …

Effects of antipsychotics on antioxidant defence system in patients with schizophrenia: a meta-analysis

XX Goh, PY Tang, SF Tee - Psychiatry Research, 2022 - Elsevier
Abstract Theory of oxidative stress is suggested in the pathophysiology of schizophrenia. To
determine the cause of impaired antioxidant defense system in schizophrenia, a meta …

N-acetylcysteine prevents olanzapine-induced oxidative stress in mHypoA-59 hypothalamic neurons

Z Boz, M Hu, Y Yu, XF Huang - Scientific Reports, 2020 - nature.com
Olanzapine is a second-generation antipsychotic (AP) drug commonly prescribed for the
treatment of schizophrenia. Recently, olanzapine has been found to cause brain tissue …

Geraniol attenuates oxidative stress, bioaccumulation, serological and histopathological changes during aluminum chloride-hepatopancreatic toxicity in male Wistar …

SM Hosseini, LB Hejazian, R Amani… - … Science and Pollution …, 2020 - Springer
Aluminum chloride (AlCl 3) has different industrial applications including manufacturing
paint and water treatment. The present study was designed to evaluate the alleviating effect …

Evaluation of cytotoxic, oxidative stress and genotoxic responses of hydroxyapatite nanoparticles on human blood cells

H Turkez, MI Yousef, E Sönmez, B Togar… - Journal of Applied …, 2014 - Wiley Online Library
The present study was designed to investigate genotoxic and cytotoxic effects and oxidative
damage of increasing concentrations of nano‐hydroxyapatite (5, 10, 20, 50, 75, 100, 150 …

Blood-based oxidation markers in medicated and unmedicated schizophrenia patients: A meta-analysis

XX Goh, PY Tang, SF Tee - Asian Journal of Psychiatry, 2022 - Elsevier
Increased reactive species due to the effect of antipsychotics on oxidative stress may be
involved in the development of schizophrenia. However, antipsychotics may have different …

Second-generation antipsychotic olanzapine attenuates behavioral and prefrontal cortex synaptic plasticity deficits in a neurodevelopmental schizophrenia-related rat …

DJ Apam-Castillejos, H Tendilla-Beltrán… - Journal of Chemical …, 2022 - Elsevier
Second-generation antipsychotics are the drugs of choice for the treatment of
neurodevelopmental-related mental diseases such as schizophrenia. Despite the …

The carvacrol ameliorates acute pancreatitis-induced liver injury via antioxidant response

M Bakır, F Geyikoglu, S Colak, H Turkez, TO Bakır… - Cytotechnology, 2016 - Springer
Acute pancreatitis (AP) may cause significant persistent multi-organ dysfunction. Carvacrol
(CAR) possesses a variety of biological and pharmacological properties. The aim of the …

Xanthoria elegans (Link) (lichen) extract counteracts DNA damage and oxidative stress of mitomycin C in human lymphocytes

H Turkez, E Aydin, A Aslan - Cytotechnology, 2012 - Springer
Several lichen species have been used for medicinal purposes throughout the ages, and
they are reported to be effective in the treatment of different disorders including ulcer and …

Protective effects of cyclosativene on H2O2-induced injury in cultured rat primary cerebral cortex cells

H Turkez, B Togar, A Di Stefano, N Taspınar, P Sozio - Cytotechnology, 2015 - Springer
Sesquiterpenes have attracted much interest with respect to their protective effect against
oxidative damage that may be the cause of many diseases including several …