Stereotactic body radiation therapy for localized prostate cancer: a systematic review and meta-analysis of over 6,000 patients treated on prospective studies

WC Jackson, J Silva, HE Hartman, RT Dess… - International Journal of …, 2019 - Elsevier
Purpose Utilization of stereotactic body radiation therapy (SBRT) for treatment of localized
prostate cancer is increasing. Guidelines and payers variably support the use of prostate …

[HTML][HTML] How low can you go? The radiobiology of hypofractionation

DH Brand, AM Kirby, JR Yarnold, N Somaiah - Clinical Oncology, 2022 - Elsevier
Hypofractionated radical radiotherapy is now an accepted standard of care for tumour sites
such as prostate and breast cancer. Much research effort is being directed towards more …

A prospective single-arm phase 2 study of stereotactic magnetic resonance guided adaptive radiation therapy for prostate cancer: early toxicity results

AME Bruynzeel, SU Tetar, SS Oei, S Senan… - International Journal of …, 2019 - Elsevier
Purpose Use of stereotactic body radiation therapy (SBRT) is increasing in patients with
localized prostate cancer, but concerns about early and late gastrointestinal (GI) and …

Personalized ultrafractionated stereotactic adaptive radiotherapy (PULSAR) in preclinical models enhances single-agent immune checkpoint blockade

C Moore, CC Hsu, WM Chen, BPC Chen, C Han… - International Journal of …, 2021 - Elsevier
Purpose Harnessing the immune-stimulatory effects of radiation by combining it with
immunotherapy is a promising new treatment strategy. However, more studies …

Mechanisms, mitigation, and management of urinary toxicity from prostate radiotherapy

JM Martin, M Richardson, S Siva, M Cardoso… - The Lancet …, 2022 - thelancet.com
Urinary toxicity is common following pelvic radiotherapy and can have a substantial negative
effect on survivorship. Due to its prevalence and the increasing number of related clinical …

Diminishing returns from ultrahypofractionated radiation therapy for prostate cancer

IR Vogelius, SM Bentzen - … Journal of Radiation Oncology* Biology* Physics, 2020 - Elsevier
Purpose More than a decade of randomized controlled trials in prostate cancer has
established a positive radiation dose response at moderate doses and a consistently low α/β …

Once‐a‐week or every‐other‐day urethra‐sparing prostate cancer stereotactic body radiotherapy, a randomized phase II trial: 18 months follow‐up results

T Zilli, S Jorcano, S Bral, C Rubio… - Cancer …, 2020 - Wiley Online Library
Background To present the 18 months results from a prospective multicenter phase II
randomized trial of short vs protracted urethra‐sparing stereotactic body radiotherapy …

[HTML][HTML] The evolving interplay of SBRT and the immune system, along with future directions in the field

M Miljanic, S Montalvo, M Aliru, T Song… - Cancers, 2022 - mdpi.com
Simple Summary We provide this commentary of stereotactic body radiotherapy (SBRT), and
describe our evolving understanding of this treatment approach, its effects on the immune …

From once-weekly to semi-weekly whole prostate gland stereotactic radiotherapy with focal boosting: Primary endpoint analysis of the multicenter phase II hypo …

L De Cock, C Draulans, FJ Pos, S Isebaert… - Radiotherapy and …, 2023 - Elsevier
Background and purpose The hypo-FLAME trial showed that once-weekly (QW) focal
boosted prostate stereotactic body radiotherapy (SBRT) is associated with acceptable acute …

[HTML][HTML] Stereotactic body radiotherapy for localized prostate cancer–5-year efficacy results

K Vuolukka, P Auvinen, E Tiainen, JE Palmgren… - Radiation …, 2020 - Springer
Background The use of stereotactic body radiotherapy (SBRT) as the primary treatment
modality in clinically localized prostate cancer (PCa) is emerging. The aim of the study was …