This review provides insights into the mechanism underlying the pathogenesis of myopia
and potential targets for clinical intervention. Although the etiology of myopia involves both …

Myopia is the most common eye disorder, caused by heterogeneous genetic and
environmental factors. Rare progressive and stationary inherited retinal disorders are often …

Purpose The dopamine (DA) system in the retina is critical to normal visual development as
lack of retinal DA signaling may contribute to myopic development. The involvement of DA in …

As one of the leading causes of visual impairment and blindness, myopia poses a significant
public health burden in Asia. The primary determinant of myopia is an elongated ocular axial …

Introduction Myopia is recognized as a progressive eye disease. The aim of this study was to
evaluate the frequency and associated factors of clinically significant axial length (AL) …

In the regulation of ocular growth, scleral events critically determine eye size and thus the
refractive status of the eye. Increased scleral matrix remodeling can lead to exaggerated eye …

Genetic and environmental factors have been shown to control visually-guided eye growth
and influence myopia development. However, investigations into the intersection of these …

Refractive eye development is a tightly coordinated developmental process. The general
layout of the eye and its various components are established during embryonic …

Atropine, a muscarinic antagonist, is known to inhibit myopia progression in several animal
models and humans. However, the mode of action is not established yet. In this study, we …

Gene expression in tree shrew choroid was examined during the development of minus-lens
induced myopia (LIM, a GO condition), after completion of minus-lens compensation (a …