Risk factors, clinical features and treatment of Behçet's disease uveitis

Z Zhong, G Su, P Yang - Progress in Retinal and Eye Research, 2023 - Elsevier
Behçet's disease is a systemic vasculitis frequently associated with intraocular inflammation.
Recent findings identified independent clinical clusters in Behçet's disease, each involving …

Activation of the interleukin-23/interleukin-17 signalling pathway in autoinflammatory and autoimmune uveitis

Z Zhong, G Su, A Kijlstra, P Yang - Progress in retinal and eye research, 2021 - Elsevier
Uveitis is a group of diseases characterized by intraocular inflammation, of which some are
driven by autoinflammatory or autoimmune responses, such as Vogt-Koyanagi-Harada …

Advances in the treatment of Behcet's disease

F Alibaz-Oner, H Direskeneli - Current rheumatology reports, 2021 - Springer
Abstract Purpose of Review To assess current management of Behcet's disease (BD).
Controversies on therapeutic approaches to different manifestations, whether conventional …

[HTML][HTML] Immunopathogenesis of Behçet's disease and treatment modalities

TB Van der Houwen, PM van Hagen… - Seminars in Arthritis and …, 2022 - Elsevier
Introduction Behçet's disease (BD) is an auto-inflammatory disease, primarily characterized
by recurrent painful mucocutaneous ulcerations. Methods A literature search was performed …

Combinations of immunomodulatory agents for prevention of uveitis relapse in patients with severe Behçet's disease already on corticosteroid therapy: a randomised …

Z Zhong, D Deng, Y Gao, Q Bu, L Dai… - The Lancet …, 2024 - thelancet.com
Background Data from head-to-head trials of immunomodulatory therapies for Behçet's
disease are scarce. We aimed to compare the efficacy and safety of ciclosporin, interferon …

TNF-α in uveitis: from bench to clinic

Q Jiang, Z Li, T Tao, R Duan, X Wang… - Frontiers in …, 2021 - frontiersin.org
Uveitis is an inflammation of the iris, ciliary body, vitreous, retina, or choroid, which has been
shown to be the first manifestation of numerous systemic diseases. Studies about the …

A contemporary review of behcet's syndrome

J Chen, X Yao - Clinical reviews in allergy & immunology, 2021 - Springer
Behcet's syndrome (BS) is a chronic systemic inflammatory vasculitis with a wide range of
clinical manifestations including recurrent oral and genital ulcers; cutaneous lesions; and …

Biotherapies in uveitis

M Leclercq, AC Desbois, F Domont, G Maalouf… - Journal of clinical …, 2020 - mdpi.com
Non-infectious uveitis (NIU) represents one of the leading causes of blindness in developed
countries. The therapeutic strategy aims to rapidly control intra-ocular inflammation, prevent …

Behçet disease: an update for dermatologists

E Alpsoy, BC Bozca, A Bilgic - American Journal of Clinical Dermatology, 2021 - Springer
Behçet disease (BD) is a chronic, relapsing, systemic vasculitis of unknown etiology with the
clinical features of oral and genital ulcers, cutaneous vasculitic lesions, ocular, articular …

[PDF][PDF] Optimisation of tocilizumab therapy in giant cell arteritis. A multicentre real-life study of 471 patients

M Calderón-Goercke, J Loricera, C Moriano… - Clin Exp …, 2023 - clinexprheumatol.org
Objective Tocilizumab (TCZ) is the only biologic therapy approved for giant cell arteritis
(GCA). There is general agreement on the initial/maintenance dose, duration of TCZ therapy …