The nuclear envelope (NE) is connected to the different types of cytoskeletal elements by
linker of nucleoskeleton and cytoskeleton (LINC) complexes. LINC complexes exist from …

Cell nuclei are physically integrated with the cytoskeleton through the linker of
nucleoskeleton and cytoskeleton (LINC) complex, a structure that spans the nuclear …

Centromere clustering during interphase is a phenomenon known to occur in many different
organisms and cell types, yet neither the factors involved nor their physiological relevance is …

Genomic architecture facilitates chromosome recognition, pairing, and recombination.
Telomeres and subtelomeres play an important role at the beginning of meiosis in specific …

Transcriptionally silent chromatin localizes to the nuclear periphery, which provides a
special microenvironment for gene repression. A variety of nuclear membrane proteins …

Background The packaging of long chromatin fibers in the nucleus poses a major challenge,
as it must fulfill both physical and functional requirements. Until recently, insights into the …

The establishment of centromere-specific CENP-A chromatin is influenced by epigenetic
and genetic processes. Central domain sequences from fission yeast centromeres are …

Faithful genome propagation requires coordination between nuclear envelope (NE)
breakdown, spindle formation, and chromosomal events. The conserved linker of …

The association of genomic loci to the nuclear periphery is proposed to facilitate cell type-
specific gene repression and influence cell fate decisions. However, the interplay between …

The formation of the nuclear envelope and the subsequent compartmentalization of the
genome is a defining feature of eukaryotes. Traditionally, the nuclear envelope was purely …