[HTML][HTML] Addressing race in pulmonary function testing by aligning intent and evidence with practice and perception
The practice of using race or ethnicity in medicine to explain differences between individuals
is being called into question because it may contribute to biased medical care and research …
is being called into question because it may contribute to biased medical care and research …
Genetics of combined pituitary hormone deficiency: roadmap into the genome era
Q Fang, AS George, ML Brinkmeier… - Endocrine …, 2016 - academic.oup.com
The genetic basis for combined pituitary hormone deficiency (CPHD) is complex, involving
30 genes in a variety of syndromic and nonsyndromic presentations. Molecular diagnosis of …
30 genes in a variety of syndromic and nonsyndromic presentations. Molecular diagnosis of …
Identification of the human skeletal stem cell
Stem cell regulation and hierarchical organization of human skeletal progenitors remain
largely unexplored. Here, we report the isolation of a self-renewing and multipotent human …
largely unexplored. Here, we report the isolation of a self-renewing and multipotent human …
[HTML][HTML] The genomic origins of the world's first farmers
The precise genetic origins of the first Neolithic farming populations in Europe and
Southwest Asia, as well as the processes and the timing of their differentiation, remain …
Southwest Asia, as well as the processes and the timing of their differentiation, remain …
The genetic architecture and evolution of the human skeletal form
The human skeletal form underlies bipedalism, but the genetic basis of skeletal proportions
(SPs) is not well characterized. We applied deep-learning models to 31,221 x-rays from the …
(SPs) is not well characterized. We applied deep-learning models to 31,221 x-rays from the …
The missing link between genetic association and regulatory function
The genetic basis of most traits is highly polygenic and dominated by non-coding alleles. It is
widely assumed that such alleles exert small regulatory effects on the expression of cis …
widely assumed that such alleles exert small regulatory effects on the expression of cis …
Novel genetic loci underlying human intracranial volume identified through genome-wide association
Intracranial volume reflects the maximally attained brain size during development, and
remains stable with loss of tissue in late life. It is highly heritable, but the underlying genes …
remains stable with loss of tissue in late life. It is highly heritable, but the underlying genes …
[HTML][HTML] Exploring the 175-year history of spirometry and the vital lessons it can teach us today
175 years have elapsed since John Hutchinson introduced the world to his version of an
apparatus that had been in development for nearly two centuries, the spirometer. Though he …
apparatus that had been in development for nearly two centuries, the spirometer. Though he …
Genetic contributions to variation in human stature in prehistoric Europe
The relative contributions of genetics and environment to temporal and geographic variation
in human height remain largely unknown. Ancient DNA has identified changes in genetic …
in human height remain largely unknown. Ancient DNA has identified changes in genetic …
Heritability within groups is uninformative about differences among groups: Cases from behavioral, evolutionary, and statistical genetics
JG Schraiber, MD Edge - Proceedings of the National …, 2024 - National Acad Sciences
Without the ability to control or randomize environments (or genotypes), it is difficult to
determine the degree to which observed phenotypic differences between two groups of …
determine the degree to which observed phenotypic differences between two groups of …