[HTML][HTML] A review on metal complexes and its anti-cancer activities: Recent updates from in vivo studies
Research into cancer therapeutics has uncovered various potential medications based on
metal-containing scaffolds after the discovery and clinical applications of cisplatin as an anti …
metal-containing scaffolds after the discovery and clinical applications of cisplatin as an anti …
Research progress on the biological activities of metal complexes bearing polycyclic aromatic hydrazones
R Liu, J Cui, T Ding, Y Liu, H Liang - Molecules, 2022 - mdpi.com
Due to the abundant and promising biological activities of aromatic hydrazones, it is of great
significance to study the biological activities of their metal complexes for the research and …
significance to study the biological activities of their metal complexes for the research and …
Coordination behavior of acylthiourea ligands in their Ru (II)–benzene complexes─ structures and anticancer activity
S Swaminathan, J Haribabu… - …, 2022 - ACS Publications
Acylthiourea ligands have applications in both synthetic and applied chemistry. The skeleton
of the ligand contains several heteroatoms which offer variable coordination modes in their …
of the ligand contains several heteroatoms which offer variable coordination modes in their …
Hinged Bipodal Furoylthiourea-Based Ru(II)-Arene Complexes: Effect of (ortho, meta, or para)-Substitution on Coordination and Anticancer Activity
We set out to design and synthesize bipodal ligands with the phenyl group as the spacer
and varied the substitution on the spacer between ortho (L1), meta (L2), and para (L3). The …
and varied the substitution on the spacer between ortho (L1), meta (L2), and para (L3). The …
Ruthenium (II)‐Dithiocarbazates as Anticancer Agents: Synthesis, Solution Behavior, and Mitochondria‐Targeted Apoptotic Cell Death
The reaction of the Ru (PPh3) 3Cl2 with HL1− 3− OH (− OH stands for the oxime hydroxyl
group; HL1− OH= diacetylmonoxime‐S‐benzyldithiocarbazonate; HL2− OH …
group; HL1− OH= diacetylmonoxime‐S‐benzyldithiocarbazonate; HL2− OH …
Influence of Indole-N Substitution of Thiosemicarbazones in Cationic Ru(II)(η6-Benzene) Complexes on Their Anticancer Activity
Indole thiosemicarbazones (TSCs) and their complexes are known to possess various
biological activities. The variation in anticancer activity with different indole-N substituents of …
biological activities. The variation in anticancer activity with different indole-N substituents of …
Platinum group metal (PGM) complexes having acylthiourea ligand system as catalysts or anticancer agents
The intention behind the design of a metal complex is quite crucial for its development
towards a particular application. Transition metal complexes have tremendously become …
towards a particular application. Transition metal complexes have tremendously become …
Synthesis and characterization of N4-substituted thiosemicarbazones: DNA/BSA binding, molecular docking, anticancer activity, ADME study and computational …
V Manakkadan, J Haribabu… - Journal of Molecular …, 2023 - Elsevier
A series of thiosemicarbazones with the general formula, R− CHdouble bondN− NH− C (S)−
R 1 [R= C 6 H 5 F & R 1= C 4 H 9 NO (TL1), R= C 8 H 10 O 2 & R 1= C 4 H 9 NO (TL2), R= C …
R 1 [R= C 6 H 5 F & R 1= C 4 H 9 NO (TL1), R= C 8 H 10 O 2 & R 1= C 4 H 9 NO (TL2), R= C …
Synthesis, spectroscopic characterizations, single crystal X-ray analysis, DFT calculations, in vitro biological evaluation and in silico evaluation studies of …
VNV Palakkeezhillam, J Haribabu… - Journal of Molecular …, 2023 - Elsevier
We created new thiosemicarbazones and their cyclized heterocyclic compounds, examined
them, and evaluated their biological activity in silico and in vitro. Two pyrene-based …
them, and evaluated their biological activity in silico and in vitro. Two pyrene-based …
Synthesis, cytotoxicity and docking studies (with SARS-CoV-2) of water-soluble binuclear Ru-p-cymene complex holding indole thiosemicarbazone ligand
A water-soluble binuclear organometallic Ru-p-cymene complex [Ru (η 6-p-cymene)(η 2-L)]
2 (1) was prepared from (E)-2-((1H-indol-3-yl) methylene)-N-phenylhydrazine-1 …
2 (1) was prepared from (E)-2-((1H-indol-3-yl) methylene)-N-phenylhydrazine-1 …