Neuronal nicotinic acetylcholine receptors (nAChRs) are a heterogeneous family of
pentameric ligand-gated cation channels that are expressed throughout the brain and …

The past decades have seen a revolution in our understanding of brain diseases and in
particular of drug addiction. This has been largely due to the identification of …

The vast diversity of GABAergic interneurons is believed to endow hippocampal
microcircuits with the required flexibility for memory encoding and retrieval. However …

Nicotine is the principal addictive component that drives continued tobacco use despite
users' knowledge of the harmful consequences. The initiation of addiction involves the …

In humans, tobacco withdrawal produces symptoms that contribute to the difficulty
associated with smoking cessation. Nicotine withdrawal symptoms can also be observed in …

Cannabis is the most frequently used illicit psychoactive substance worldwide; around one
in ten users become dependent. The risk for cannabis use disorder (CUD) has a strong …

Neuronal cholinergic nicotinic receptors (nAChRs) are a heterogeneous class of cationic
channels that are widely distributed in the nervous system that have specific functional and …

Despite recent advances in understanding the causes of epilepsy, especially the genetic,
comprehending the biological mechanisms that lead to the epileptic phenotype remains …

Progress has been made over the last decade in our understanding of the brain areas and
circuits involved in nicotine reward and withdrawal, leading to models of addiction that …

Renshaw cell properties have been studied extensively for over 50 years, making them a
uniquely well‐defined class of spinal interneuron. Recent work has revealed novel ways to …