The incidence of nearly all AIDS-defining opportunistic infections (OIs) decreased
significantly in the United States in the years 1992–1998; decreases in the most common …

HIV/AIDS not only represents the most severe epidemic in modern times, but also the
greatest public health challenge in history. The response of the scientific community has …

Background Contemporary antiretroviral therapies (ART) and management strategies have
diminished both human immunodeficiency virus (HIV) treatment failure and the acquired …

Resistance to antiretroviral drugs remains an important limitation to successful human
immunodeficiency virus type 1 (HIV-1) therapy. Resistance testing can improve treatment …

ContextGuidelines for antiretroviral therapy are important for clinicians worldwide given the
complexity of the field and the varied clinical situations in which these agents are used. The …

We have established a panel of human monoclonal antibodies against human
immunodeficiency virus type 1 (HIV-1). The antibodies 2F5 and 2G12 have been identified …

Although combination antiretroviral therapy has resulted in a considerable improvement in
the treatment of human immunodeficiency virus (HIV) type 1 (HIV-1) infection, the …

Objective To update recommendations for antiretroviral therapy for adult human
immunodeficiency virus type 1 (HIV-1) infection, based on new information and drugs that …

The use of chemotherapy to suppress replication of the human immunodeficiency virus (HIV)
has transformed the face of AIDS in the developed world. Pronounced reductions in illness …

Dideoxynucleosides, which are potent inhibitors of HIV reverse transcriptase and other viral
DNA polymerases, are a common component of highly active anti-retroviral therapy …