Zinc oxide nanoparticles induce oxidative and proteotoxic stress in ovarian cancer cells and trigger apoptosis independent of p53-mutation status

A Padmanabhan, M Kaushik, R Niranjan… - Applied surface …, 2019 - Elsevier
Ovarian cancer continues to be the most lethal among gynecological malignancies and the
major cause for cancer-associated mortality among women. Limitations of current ovarian …

Regulating NKX3. 1 stability and function: Post‐translational modifications and structural determinants

A Padmanabhan, V Rao, AM De Marzo… - The …, 2016 - Wiley Online Library
BACKGROUND The androgen‐regulated homeodomain transcription factor NKX3. 1 plays
roles in early prostate development and functions as a prostate‐specific tumor suppressor …

TiO2 nanocomposite for the controlled release of drugs against pathogens causing wound infections

GD Venkatasubbu, S Nagamuthu… - Materials Research …, 2018 - iopscience.iop.org
Chitosan titanium dioxide nanocomposite has been used for wound healing. Titanium
dioxide (TiO 2) nanoparticles are synthesised and made in to nanocomposite along with …

[PDF][PDF] Targeting Protein Kinase Substrate Docking in Cancers

A Padmanabhan - Journal of Glycobiology, 2014 - researchgate.net
Cancers are characterized by uncontrolled cell growth, increased cell survival, remodeling
of tumor microenvironment, neovascularization, invasion and metastasis. Each of these …

[PDF][PDF] Drugging protein kinases in cancer: from small molecules to nanoparticles

VG Devanand - MOJ Proteomics Bioinform, 2017 - academia.edu
Protein kinases are a large family of enzymes that catalyze the transfer of a phosphate group
from adenosine triphosphate (ATP) to the hydroxyl (OH) group of an amino acid side chain …

[PDF][PDF] Methods to Profile Protien Kinase Substrates in Cells

SH Venkatesha - MOJ Proteomics Bioinform, 2016 - researchgate.net
Protein kinases and protein phosphorylation play an important role in almost every process
within a cell. Identifying specific substrates downstream of individual protein kinases is …

[PDF][PDF] A New Garbage Disposal System–Cancer Cells Unveils A New Trick

VR Elangovan - MOJ Proteomics Bioinform, 2016 - researchgate.net
Proteasomes play an important role in maintaining cellular homeostasis by degrading
unwanted and misfolded proteins in cells through regulated proteolysis. The increased …

[引用][C] Journal of Glycobiology