Multifunctional role of polyvinylpyrrolidone in pharmaceutical formulations

Y Luo, Y Hong, L Shen, F Wu, X Lin - AAPS PharmSciTech, 2021 - Springer
Abstract Polyvinylpyrrolidone (PVP), a non-ionic polymer, has been employed in multifarious
fields such as paper, fibers and textiles, ceramics, and pharmaceutics due to its superior …

[HTML][HTML] Pharmaceutical dispersion techniques for dissolution and bioavailability enhancement of poorly water-soluble drugs

X Zhang, H Xing, Y Zhao, Z Ma - Pharmaceutics, 2018 - mdpi.com
Over the past decades, a large number of drugs as well as drug candidates with poor
dissolution characteristics have been witnessed, which invokes great interest in enabling …

Piperine-loaded electrospun nanofibers, an implantable anticancer controlled delivery system for postsurgical breast cancer treatment

D Babadi, S Dadashzadeh, Z Shahsavari… - International Journal of …, 2022 - Elsevier
Tumorectomy followed by radiotherapy, hormone, and chemotherapy, are the current
mainstays for breast cancer treatment. However, these strategies have systemic toxicities …

[HTML][HTML] Enhanced anticancer response of curcumin-and piperine-loaded lignin-gp (NIPAM-co-DMAEMA) gold nanogels against U-251 MG glioblastoma multiforme

B Javed, X Zhao, D Cui, J Curtin, F Tian - Biomedicines, 2021 - mdpi.com
Glioblastoma multiforme (GBM) is the most aggressive and commonly diagnosed brain
cancer and is highly resistant to routine chemotherapeutic drugs. The present study involves …

[HTML][HTML] Improved solubility and dissolution rates in novel multicomponent crystals of piperine with succinic acid

E Zaini, Afriyani, L Fitriani, F Ismed, A Horikawa… - Scientia …, 2020 - mdpi.com
The objectives of this study were to prepare and characterize a novel piperine–succinic acid
multicomponent crystal phase and to evaluate the improvement in the solubility and …

Solid dispersion technology as a formulation strategy for the fabrication of modified release dosage forms: A comprehensive review

K Patel, S Shah, J Patel - DARU Journal of Pharmaceutical Sciences, 2022 - Springer
Solubility limited bioavailability is one of the crucial parameters that affect the formulation
development of the new chemical entities. Thus the major constraint in the pharmaceutical …

[HTML][HTML] Hot-melt extrusion as an effective technique for obtaining an amorphous system of curcumin and piperine with improved properties essential for their better …

K Wdowiak, R Pietrzak, E Tykarska, J Cielecka-Piontek - Molecules, 2023 - mdpi.com
Poor bioavailability hampers the use of curcumin and piperine as biologically active agents.
It can be improved by enhancing the solubility as well as by using bioenhancers to inhibit …

Solubility, molecular interactions and mixing thermodynamic properties of piperine in various pure solvents at different temperatures

S Alshehri, N Haq, F Shakeel - Journal of Molecular Liquids, 2018 - Elsevier
In this study, the solubility, molecular interactions and mixing thermodynamic properties of a
poorly water soluble bioactive compound piperine in twelve different pure solvents namely …

Quality by design–based development and optimization of fourth-generation ternary solid dispersion of standardized Piper longum extract for melanoma therapy

D Mohapatra, DN Kumar, S Shreya, V Pandey… - Drug Delivery and …, 2023 - Springer
The study aimed to enhance the solubility, dissolution, and oral bioavailability of
standardized Piper longum fruits ethanolic extract (PLFEE) via fourth-generation ternary …

[PDF][PDF] In vitro evaluation of nanoemulsions of curcumin, piperine, and tualang honey as antifungal agents for candida species

ZX Phuna, JKE Yu, JY Tee, SQ Chuah… - Journal of Applied …, 2020 - biotechrep.ir
Introduction: Vulvovaginal candidiasis (VVC) has received enormous attention, not only due
to its negative influences on women's life but also because of the escalating trend of fungal …