Fertility preservation in boys: recent developments and new insights

E Goossens, K Jahnukainen, RT Mitchell… - Human …, 2020 - academic.oup.com
BACKGROUND Infertility is an important side effect of treatments used for cancer and other
non-malignant conditions in males. This may be due to the loss of spermatogonial stem cells …

Exposure to chemotherapy during childhood or adulthood and consequences on spermatogenesis and male fertility

M Delessard, J Saulnier, A Rives, L Dumont… - International journal of …, 2020 - mdpi.com
Over the last decade, the number of cancer survivors has increased thanks to progress in
diagnosis and treatment. Cancer treatments are often accompanied by adverse side effects …

[HTML][HTML] Fertility preservation in patients undergoing gonadotoxic therapy or gonadectomy: a committee opinion

Practice Committee of the American Society for … - Fertility and …, 2019 - Elsevier
Patients preparing to undergo gonadotoxic medical therapy, radiation therapy, or
gonadectomy should be provided with prompt counseling regarding available options for …

Spermatogonial stem cells for in vitro spermatogenesis and in vivo restoration of fertility

F Ibtisham, A Honaramooz - Cells, 2020 - mdpi.com
Spermatogonial stem cells (SSCs) are the only adult stem cells capable of passing genes
onto the next generation. SSCs also have the potential to provide important knowledge …

What should be done in terms of fertility preservation for patients with cancer? The French 2021 guidelines

N Rives, B Courbière, T Almont, D Kassab… - European Journal of …, 2022 - Elsevier
Aim To provide practice guidelines about fertility preservation (FP) in oncology. Methods We
selected 400 articles after a PubMed review of the literature (1987–2019) …

Engineered reproductive tissues

ES Gargus, HB Rogers, KE McKinnon… - Nature biomedical …, 2020 - nature.com
Engineered male and female biomimetic reproductive tissues are being developed as
autonomous in vitro units or as integrated multi-organ in vitro systems to support germ cell …

Fertility preservation for prepubertal boys: lessons learned from the past and update on remaining challenges towards clinical translation

C Wyns, M Kanbar, MG Giudice… - Human reproduction …, 2021 - academic.oup.com
BACKGROUND Childhood cancer incidence and survivorship are both on the rise.
However, many lifesaving treatments threaten the prepubertal testis. Cryopreservation of …

Male fertility preservation and restoration strategies for patients undergoing gonadotoxic therapies

KTD Tran, H Valli-Pulaski, A Colvin… - Biology of …, 2022 - academic.oup.com
Medical treatments for cancers or other conditions can lead to permanent infertility. Infertility
is an insidious disease that impacts not only the ability to have a biological child but also the …

Generation of organized porcine testicular organoids in solubilized hydrogels from decellularized extracellular matrix

M Vermeulen, F Del Vento, M Kanbar… - International Journal of …, 2019 - mdpi.com
Cryopreservation of immature testicular tissue (ITT) prior to chemo/radiotherapy is now
ethically accepted and is currently the only way to preserve fertility of prepubertal boys about …

3D bioprinting for organ and organoid models and disease modeling

AC Juraski, S Sharma, S Sparanese… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction 3D printing, a versatile additive manufacturing technique, has diverse
applications ranging from transportation, rapid prototyping, clean energy, and medical …