MicroRNAs in the pathogenesis of hepatocellular carcinoma: A review

A Morishita, K Oura, T Tadokoro, K Fujita, J Tani… - Cancers, 2021 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is one of the most frequently occurring
cancers, and the prognosis for late-stage HCC remains poor. A better understanding of the …

MicroRNA biomarkers in IBD—differential diagnosis and prediction of colitis-associated cancer

JP James, LB Riis, M Malham, E Høgdall… - International journal of …, 2020 - mdpi.com
Inflammatory bowel disease (IBD) includes Crohn's disease (CD) and ulcerative colitis (UC).
These are chronic autoimmune diseases of unknown etiology affecting the gastrointestinal …

LncRNA HULC triggers autophagy via stabilizing Sirt1 and attenuates the chemosensitivity of HCC cells

H Xiong, Z Ni, J He, S Jiang, X Li, W Gong, L Zheng… - Oncogene, 2017 - nature.com
Considerable evidences have shown that autophagy has an important role in tumor
chemoresistance. However, it is still unknown whether the lncRNA HULC (highly …

The circular RNA Cdr1as act as an oncogene in hepatocellular carcinoma through targeting miR-7 expression

L Yu, X Gong, L Sun, Q Zhou, B Lu, L Zhu - PloS one, 2016 - journals.plos.org
CircRNAs are a class of endogenous RNA that regulates gene expression at the post-
transcriptional or transcriptionallevel through interacting with other molecules or microRNAs …

A serum microRNA classifier for early detection of hepatocellular carcinoma: a multicentre, retrospective, longitudinal biomarker identification study with a nested case …

XJ Lin, Y Chong, ZW Guo, C Xie, XJ Yang… - The Lancet …, 2015 - thelancet.com
Background The ability of circulating microRNAs (miRNAs) to detect preclinical
hepatocellular carcinoma has not yet been reported. We aimed to identify and assess a …

Integrative data analysis of multi-platform cancer data with a multimodal deep learning approach

M Liang, Z Li, T Chen, J Zeng - IEEE/ACM transactions on …, 2014 - ieeexplore.ieee.org
Identification of cancer subtypes plays an important role in revealing useful insights into
disease pathogenesis and advancing personalized therapy. The recent development of high …

The emerging and diverse roles of sirtuins in cancer: a clinical perspective

H Yuan, L Su, WY Chen - OncoTargets and therapy, 2013 - Taylor & Francis
Sirtuins are a highly conserved family of nicotinamide adenine dinucleotide (NAD+)-
dependent protein lysine modifying enzymes with deacetylase, adenosine …

Intestinal microbiota and miRNA in IBD: a narrative review about discoveries and perspectives for the future

ECS Oliveira, AEV Quaglio, DO Magro… - International Journal of …, 2023 - mdpi.com
Inflammatory bowel disease (IBD) includes Crohn's disease (CD) and ulcerative colitis (UC)
and comprises a chronic gastrointestinal tract disorder characterized by hyperactive and …

Resveratrol's anti-cancer effects through the modulation of tumor glucose metabolism

A Brockmueller, S Sameri, A Liskova, K Zhai… - Cancers, 2021 - mdpi.com
Simple Summary The prevention and treatment of cancer is an ongoing medical challenge.
In the context of personalized medicine, the well-studied polyphenol resveratrol could …

MicroRNA-29c mediates initiation of gastric carcinogenesis by directly targeting ITGB1

TS Han, K Hur, G Xu, B Choi, Y Okugawa, Y Toiyama… - Gut, 2015 - gut.bmj.com
Objective Gastric cancer (GC) remains difficult to cure due to heterogeneity in a clinical
challenge and the molecular mechanisms underlying this disease are complex and not …