Regression of cardiac hypertrophy in health and disease: mechanisms and therapeutic potential
TG Martin, MA Juarros, LA Leinwand - Nature Reviews Cardiology, 2023 - nature.com
Left ventricular hypertrophy is a leading risk factor for cardiovascular morbidity and mortality.
Although reverse ventricular remodelling was long thought to be irreversible, evidence from …
Although reverse ventricular remodelling was long thought to be irreversible, evidence from …
Cardiovascular risk factors during pregnancy impact the postpartum cardiac and vascular reverse remodeling
AF Ferreira, MJ Azevedo, J Morais… - American Journal …, 2023 - journals.physiology.org
Pregnant women with cardiovascular risk (CVR) factors are highly prone to develop
cardiovascular disease later in life. Thus, recent guidelines suggest extending the follow-up …
cardiovascular disease later in life. Thus, recent guidelines suggest extending the follow-up …
Cardiac extracellular matrix modification as a therapeutic approach
ML Hall, BM Ogle - Cardiac Extracellular Matrix: Fundamental Science to …, 2018 - Springer
The cardiac extracellular matrix (cECM) is comprised of proteins and polysaccharides
secreted by cardiac cell types, which provide structural and biochemical support to …
secreted by cardiac cell types, which provide structural and biochemical support to …
Cardioprotection of salvianolic acid B and ginsenoside Rg1 combination on subacute myocardial infarction and the underlying mechanism
Y Li, L Wang, Z Dong, S Wang, L Qi, K Cho, Z Zhang… - Phytomedicine, 2019 - Elsevier
Background Following myocardial infarction (MI), a series of structural and functional
changes evolves in the myocardium, collectively defined as cardiac remodeling. Purpose …
changes evolves in the myocardium, collectively defined as cardiac remodeling. Purpose …
Mechanisms of myocardial reverse remodelling and its clinical significance: A scientific statement of the ESC Working Group on Myocardial Function
I Falcão‐Pires, AF Ferreira, F Trindade… - European Journal of …, 2024 - Wiley Online Library
Cardiovascular disease (CVD) is the leading cause of morbimortality in Europe and
worldwide. CVD imposes a heterogeneous spectrum of cardiac remodelling, depending on …
worldwide. CVD imposes a heterogeneous spectrum of cardiac remodelling, depending on …
Tissue inhibitor of metalloproteinase-4 deletion in mice impacts maternal cardiac function during pregnancy and postpartum
AA Thurstin, AN Egeli, EC Goldsmith… - American Journal …, 2023 - journals.physiology.org
Reversible physiological cardiac hypertrophy of the maternal heart occurs during pregnancy
and involves extracellular matrix (ECM) remodeling. Previous mouse studies revealed that …
and involves extracellular matrix (ECM) remodeling. Previous mouse studies revealed that …
Inhibition of microRNA‐132 attenuates inflammatory response and detrusor fibrosis in rats with interstitial cystitis via the JAK‐STAT signaling pathway
YJ Song, JY Cao, Z Jin, WG Hu, RH Wu… - Journal of Cellular …, 2019 - Wiley Online Library
Interstitial cystitis (IC) is a heterogeneous syndrome with unknown etiology, and microRNAs
(miRs) were found to be involved in IC. In our study, we aim to explore the role of miR‐132 in …
(miRs) were found to be involved in IC. In our study, we aim to explore the role of miR‐132 in …
Stretch-induced compliance mechanism in pregnancy-induced cardiac hypertrophy and the impact of cardiovascular risk factors
AF Ferreira, MJ Azevedo, J Morais… - American Journal …, 2024 - journals.physiology.org
Pressure overload-induced hypertrophy compromises cardiac stretch-induced compliance
(SIC) after acute volume overload (AVO). We hypothesized that SIC could be enhanced by …
(SIC) after acute volume overload (AVO). We hypothesized that SIC could be enhanced by …
Effect of vitamin C on collagen structure of cardinal and uterosacral ligaments during pregnancy
RB Findik, F Ilkaya, S Guresci, H Guzel… - European Journal of …, 2016 - Elsevier
Objective This study aimed to investigate changes in collagen structure in the cardinal and
uterosacral ligaments of rats that were administered vitamin C during pregnancy. Study …
uterosacral ligaments of rats that were administered vitamin C during pregnancy. Study …
Maternal cardiac messenger RNA expression of extracellular matrix proteins in mice during pregnancy and the postpartum period
ME Parrott, E Aljrbi, DL Biederman… - Experimental …, 2018 - journals.sagepub.com
Pregnancy creates a condition of cardiac volume overload which leads to physiological
eccentric hypertrophy of the heart that is reversed in the postpartum period. Pathological …
eccentric hypertrophy of the heart that is reversed in the postpartum period. Pathological …