SRC homology 3 (SH3) domains are fundamental modules that enable the assembly of
protein complexes through physical interactions with a pool of proline-rich/noncanonical …

Classical swine fever virus (CSFV) is a highly pathogenic RNA virus belonging to the
Flaviviridae family that can cause deadly classical swine fever (CSF) in pigs. However, the …

Endocytosis of cell surface receptors is essential for cell migration and cancer metastasis.
Rab5, a small GTPase of the Rab family, is a key regulator of endosome dynamics and thus …

Neurite outgrowth is a fundamental process in neurons that produces extensions and,
consequently, neural connectivity. Neurite damage and atrophy are observed in various …

Alzheimer's disease (AD), a common form of dementia, is caused in part by the aggregation
and accumulation in the brain of amyloid β (Aβ), a product of the proteolytic cleavage of …

Arteriovenous malformation of the brain (bAVM) is a vascular phenotype related to brain
defective angiogenesis. Involved vessels show impaired expression of vascular …

Arp2/3 complex nucleates branched actin filaments that drive processes like endocytosis
and lamellipodial protrusion. WISH/DIP/SPIN90 (WDS) proteins form a class of Arp2/3 …

A number of recent research studies related to the significantly important intra-arterial
perivascular drainage pathway indicates its crucial role in maintaining the optimal brain …