Background Mood disorders, including major depressive disorder, are among the main
causes of disability and early mortality and constitute an important public health problem …

Background Transcranial direct current stimulation (tDCS) is a promising
nonpharmacological intervention for treating depression. We aimed to provide an updated …

Background: Ayahuasca is a traditional Amazon brew and its potential antidepressant
properties have recently been explored in scientific settings. We conducted a double-blind …

Multiple studies show an association between inflammatory markers and major depressive
disorder (MDD). People with chronic low-grade inflammation may be at an increased risk of …

To reduce prevalence, it is essential to narrow the treatment gaps, provide timely
interventions and high-quality treatment, eradicate waiting lists, prescribe antidepressants …

Aging is associated with complex biological changes that can be accelerated, slowed, or
even temporarily reversed by biological and non-biological factors. This article focuses on …

Treatment of depression is hampered by the failure to identify distinct symptom profiles with
distinct pathophysiologies that differentially respond to distinct treatments. We posit that …

A growing number of studies are pointing out the need for a conceptual shift from a brain-
centered to a body-inclusive approach in mental health research. In this perspective, the link …

Major depressive disorder affects approximately 8.4% of the United States population. The
World Health Organization estimates that 280 million adults worldwide are suffering from …

The prevalence of depressive disorders is growing worldwide, notably due to stagnation in
the development of drugs with greater antidepressant efficacy, the continuous large …